Team:Evry/LogisticFunctions

From 2013.igem.org

Iron coli project

Logistic functions

When we started to model biological behaviors, we realised very soon that we were going to need a function that simulates a non-exponential evolution, that would include a simple speed control and a maximum value. A smooth step function.

Such functions, named logistic functions were introduced around 1840 by M. Verhulst.

These functions looked perfect, but we needed more control : we needed to set a starting value and a precision.

Parameters:

  • Q : Magnitude.
             The limit of g as x approaches infinity is Q.
  • d : Threshold.
             The value of x from which we consider the start of the phenomenon.
  • p : Precision.
           Since the function never reaches 0 nor Q, we have to set an approximation for 0 or Q.
  • k : Efficiency.
             This parameter influences the length of the phenomenon.

Differential form:

Let the following be a Cauchy problem:

The solution of this Cauchy problem is as below:

Here is our logistic function. Yet, differential equations are not always time-related.
Let x be a temporal function, and y be a x-related logistic function. In order to integrate y into a temporal ODE, we need to write it differently:

But this equation can't be integrated in a temporal system like other equations. Because y depend on x. In our model, x is a state variable of the system. To implement this equation, we solve it before the entire system.