Team:BIT/project hardware

From 2013.igem.org

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      <td width="814" class="t1"><p class="aaa"><span class="aaa"><span class="aaa">BIT's measurement</span></span></p>
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      <td width="814" class="t1"><p class="aaa"><span class="aaa"><span class="aaa">BIT's </span></span><span class="high">measurement</span></p>
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           <p class="high"><span class="aaa"><span class="aaa"><span class="aaa">Based on</span> </span></span><span class="aaa"></span>Standard Biomedical Bricks</p>
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           <p class="high"><span class="aaa"><span class="aaa"><span class="aaa">Based on</span> </span></span><a href="#sbb" class="high">Standard Biomedical Bricks</a></p>
           <p class="high">&nbsp;</p></td>
           <p class="high">&nbsp;</p></td>
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      <td class="t2"><p>Ok , Now we have contributed a new sensor ,  put forward a concept of <a href="https://2013.igem.org/Team:BIT/project_AC">controlled amplifier</a> and are working on optimizing it .But  we think this is just a start ,for we can then use this kind of idea to detect  nearly all kinds of antibiotics in the future and we are still trying our best  to do so . </p>
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      <td class="t2"><p><span class="high">Measurement</span>:</p>
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           <p>But a matter is that we can not see the florescence in normal condition ,just like the picture below ,we need UV light , narrowband filter and light sensor to tell us the specific intensity of the light ,we also need to calculate the material we want to detect using our model . that's so complicated .</p></td>
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        <p>&nbsp; &nbsp; &nbsp;Ok , Now we have contributed a new sensor ,  put forward a concept of <a href="https://2013.igem.org/Team:BIT/project_AC">controlled amplifier</a> and are working on optimizing it .But  we think this is just a start ,for we can then use this kind of idea to detect  nearly all kinds of antibiotics in the future and we are still trying our best  to do so . </p>
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           <p>&nbsp; &nbsp; &nbsp;But a matter is that we can not see the florescence in normal condition ,just like the picture below ,we need UV exiting light , narrowband filter and light sensor to tell us the specific intensity of the light ,we also need to calculate the material we want to detect using our mathematical model . that's so complicated .</p></td>
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      <td class="t3"><p><img src="https://static.igem.org/mediawiki/2013/d/d1/BITsam.jpg" alt="" width="350"></p>
      <td class="t3"><p><img src="https://static.igem.org/mediawiki/2013/d/d1/BITsam.jpg" alt="" width="350"></p>
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        <p class="t2">here , a small, cheap and handheld device , together with our <a href="https://2013.igem.org/Team:BIT/project_microchip">micro chip</a> , is produced which together with our biological core ,forms a complete detecting system.         </p>
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        <p class="t2">&nbsp; &nbsp; &nbsp;here , a small, cheap and handheld device , together with our <a href="https://2013.igem.org/Team:BIT/project_microchip">micro chip</a> , is produced which together with our biological core ,forms a complete detecting system.         </p>
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            <td><span class="t2"><img src="https://static.igem.org/mediawiki/2013/c/cd/BITsys.jpg" alt="" width="819"></span></td>
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        <p class="t2">The small device uses normal color sensors and light path similar to UV spectrophotometer , but contains  a new ,or rather strange mathematical model . a combination of our biological  model and relative non-biological equations . </p>
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        <p class="t2"><span class="aaa"><span class="high"><span class="t2">Parameters of the system:</span></span></span></p>
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            <p class="t2">&nbsp;&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Cost: 260RMB/$40 (device &amp; chip) . </p>
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            <p class="t2">&nbsp;&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Size: 10cmX6.5cmX5cm</p>
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            <p class="t2">&nbsp;&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Power: 20W Max , 3W Average</p>
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            <p class="t2">&nbsp;&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Functions: User-define mathematical model . Fast detection . Temperature &nbsp;&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;  &nbsp;&nbsp;Control . </p>
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            <p class="t2">&nbsp;&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Resolution: 5 ng/ml Standard fluorescein sodium , 2~5ng/ml Tet .</p>
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<p class="t2">&nbsp; &nbsp; &nbsp;The small device uses normal color sensors and light path similar to UV spectrophotometer , but contains  a new ,or rather strange mathematical model . a combination of our biological  model and relative non-biological equations . </p>
        <p class="t2"><img src="https://static.igem.org/mediawiki/2013/7/77/BITthe.jpg" width="701" height="365"></p>
        <p class="t2"><img src="https://static.igem.org/mediawiki/2013/7/77/BITthe.jpg" width="701" height="365"></p>
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        <p class="t2">For the specific Data of the measure system , please click <a href="https://2013.igem.org/Team:BIT/project_data">Here.</a>         </p>
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        <p class="t2">&nbsp; &nbsp; &nbsp;For the specific Data of the measure system , please click <a href="https://2013.igem.org/Team:BIT/project_data">Here.</a>         </p>
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        <p class="t2">&nbsp;</p>
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        <p class="t2"><span class="high">Standard Biomedical Bricks (if you have interest)</span><a name="sbb"></a></p>
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        <p class="t2">&nbsp; &nbsp; &nbsp;Well , as for biological detection of harmful materials , such as <span class="aaas"><span class="ww">antibiotics , heavy metals , Aromatic hydrocarbons ,radioactive substances , Pesticide residues</span></span> and so on , we need a biological output in <span class="ww">color , fluroscence , Conductivity , OD value </span>and many other forms .</p>
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        <p class="t2"><img src="https://static.igem.org/mediawiki/2013/4/43/BITaa.gif" width="700" height="500"></p>
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        <p class="t2">&nbsp; &nbsp; &nbsp;But those outputs may be so weak , just like our fluorescence , without the <a href="https://2013.igem.org/Team:BIT/project_AC" class="ww">controlled amplifier</a> , it can hardly be seen by our eyes ,even under UV light .</p>
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        <p class="t2">&nbsp; &nbsp; &nbsp;Biomedical machines are used in this case , but  those machines can hardly be found out of the lab .</p>
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        <p class="t2">&nbsp; &nbsp; &nbsp; So we put forward <span class="high"><span class="ww">standard biomedical &amp; biological system </span></span>,that is : To design a biological core , finishing the corresponding mathematical model , and a standard biomedical external device . </p>
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        <p class="t2">&nbsp; &nbsp; &nbsp;Just like us , our aim is <span class="ww"><span class="aaa"><span class="ww">Practical Application</span></span></span> . We created a biosensor , an amplifier and their mathematical models . </p>
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        <p class="t2">&nbsp; &nbsp; &nbsp;<span class="ww">Standard biomedical bricks</span> means the specific mathematical models which suits for our low cost sensors .iGEM is an application-oriented contest , so detection needs to be economic and convenient . Now we have many standard electronic sensors , BIT iGEM team has also optimized a processor which has an interface  suiting for any kinds of sensors .<span class="ww">what we need to do</span> is to <span class="ww"><span class="t2"><span class="aaa"><span class="ww">build up our engineered bacteria</span></span></span></span>,<span class="ww"> burn the standard mathematical models in the processor</span> and <span class="ww">connect the suitable sensor to the processor</span> . then a complete and application-oriented system is built.just like our detecting system ,we have made many editions :</p>
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        <p class="t2"><img src="https://static.igem.org/mediawiki/2013/f/f6/BITqjf.jpg" width="700" height="470"></p>
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        <p class="t2">&nbsp; &nbsp; &nbsp;Then we arrange user-friendly I/O interface to the standard processor ,making a colorful cover to the whole system . that means ,you can achieve any kinds of detection using the same device ,that sounds cool ,isn't it ? .</p>
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        <p class="t2"><img src="https://static.igem.org/mediawiki/2013/0/06/BITaaa.jpg" width="700" height="442"></p>
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        <p class="t2">&nbsp; &nbsp; &nbsp;So  what we have done at this time is just to simplify the old measurement and  provide a new , convenient ,economic measurement which detection can be  achieved in kichen . maybe ,some years later ,you can see a &quot;bio-antibiotic detector&quot; in supermarket ,and let's wait for the coming of that day !</p>
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        <p class="t2">&nbsp; &nbsp; &nbsp;We have put forward a concept , and now we have make part  of the concept into reality . we will go further on our way to overcome any difficulties ,and we eagerly need partners to fight with us . If you have interest in it </p>
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Revision as of 06:42, 27 October 2013

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