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Team:Ciencias-UNAM
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| - | <div id="u54_rtf"><p style="text-align:left;"><span style="font-family:Arial;font-size:13px;font-weight:normal;font-style:normal;text-decoration:none;color:#666666;"> | + | <div id="u54_rtf"><p style="text-align:left;"><span style="font-family:Arial;font-size:13px;font-weight:normal;font-style:normal;text-decoration:none;color:#666666;">We designed a synthetic system in <i>E. coli</i> to express an antimicrobial peptide (Cathelicidin LL-37) <i>in vivo</i> only in the presence of a quorum sensing molecule (AI-2) and expel it with an efflux pump in order to act against targeted gastrointestinal pathogens. This is an effort to explore alternatives were some drug administration issues could be solved with Synthetic Biology.</span></p></div> |
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Revision as of 22:51, 21 September 2013
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We designed a synthetic system in E. coli to express an antimicrobial peptide (Cathelicidin LL-37) in vivo only in the presence of a quorum sensing molecule (AI-2) and expel it with an efflux pump in order to act against targeted gastrointestinal pathogens. This is an effort to explore alternatives were some drug administration issues could be solved with Synthetic Biology.
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Praesent libero arcu, convallis et dapibus sit amet, aliquet nec nibh. Nulla eu aliquam orci. Phasellus vitae nunc ut urna tincidunt accumsan vel ac dui. Donec tempus quis quam vitae ultrices. Vestibulum congue nec odio eget dictum. Sed tincidunt velit enim. Fusce metus augue, lobortis eget viverra sit amet, fringilla.
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