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                 White and brown adipose tissues (WAT and BAT) serve important opposite functions in overall energy balance. While WAT is specialized in energy storage in the form of triacylglycerols, BAT functions to dissipate energy in the form of heat (thermogenesis).BAT possess abundant mitochondria with uncoupling proteins 1(UCP1). UCP1 is a 6-transmembrane protein in inner mitochondria membrane, and it has been proposed to constitute three symmetrical membrane-spanning “Us”, each comprising about 100 amino acids(fig.1).The functional UCP is believed to be dimer.
                 White and brown adipose tissues (WAT and BAT) serve important opposite functions in overall energy balance. While WAT is specialized in energy storage in the form of triacylglycerols, BAT functions to dissipate energy in the form of heat (thermogenesis).BAT possess abundant mitochondria with uncoupling proteins 1(UCP1). UCP1 is a 6-transmembrane protein in inner mitochondria membrane, and it has been proposed to constitute three symmetrical membrane-spanning “Us”, each comprising about 100 amino acids(fig.1).The functional UCP is believed to be dimer.
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                 (fig.1 The protein (33kDa,306 amino acids) contains six transmembrane alpha-helices, proposed to constitute three symmetric repeats.)
                 (fig.1 The protein (33kDa,306 amino acids) contains six transmembrane alpha-helices, proposed to constitute three symmetric repeats.)

Revision as of 11:36, 27 September 2013

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