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From 2013.igem.org

Stanford-Brown iGEM

Project Descriptions: BioWires - We seek to utilize recent advances in nucleic acid chemistry to replace hydrogen bonds between mismatched DNA bases with cations. A kelation event has been described for mismatched pyrimidines, and we have selected a C-Ag+-C bond for silver's uniquely powerful conductivity. We will rigorously test the structural and thermodynamic properties of this bonding system. Our hope is to show that silver kelation by cytosine mismatches is able to enhance the conductivity of DNA. By engineering cytosine mismatches into synthetic oligonucleotide duplexes, we seek to establish a reliable platform for nanowire and nanodevice assembly. We will design and test various nucleic acid secondary structures, and hope to ultimately produce a DNA-based nanowire system that is conductive enough to be utilized in microchip design and other bioengineering applications. I'm A Badass Caption: I can haz links, style or anything that is valid markup :)