Team:Westminster

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==Westminster iGEM - Hitbug==
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After World War II strong pesticides such as DDT and chlordane were widely used. Bed bugs almost disappeared completely over several decades because these pesticides were heavily used. Bed bug infestations were limited, and bed bugs were no longer considered a major pest. Eventually, these pesticides were proven harmful to people's health and the environment and as a result there use was prohibited. The absence and resistance to some of the pesticides combined with people migrating from country to country resulted in bed bug infestations increasing. Serratia marcescens, a member of the Enterobacteriaceae is reported as a highly efficient chitin degrader. We aim to use three chitinase genes obtained from S. marcescens in designing a chitin degrading E. coli. The bugs will be subjected to the E. coli via an artificial feeding device.
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After World War II strong pesticides such as DDT and chlordane were widely used. Bed bugs almost disappeared completely over several decades because these pesticides were heavily used. Bed bug infestations were limited, and bed bugs were no longer considered a major pest. Eventually, these pesticides were proven harmful to people's health and the environment and as a result their use was prohibited. The absence and resistance to some of the pesticides combined with an increase in cross-continental travel has resulted in bed bug infestations increasing. The current methods which include human friendly pesticides, heat treatment and organics such as oils which the bugs find intolerable are not affective. Our novel approach uses ''Serratia marcescens'', a member of the Enterobacteriaceae. It is reported as a highly efficient chitin degrader. We aim to use three chitinase genes obtained from ''S. marcescens'' in designing a chitin degrading ''E. coli''. The bugs will be exposed to the ''E. coli'' via an artificial feeding device.

Revision as of 20:06, 21 August 2013

Westminster iGEM - Hitbug

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After World War II strong pesticides such as DDT and chlordane were widely used. Bed bugs almost disappeared completely over several decades because these pesticides were heavily used. Bed bug infestations were limited, and bed bugs were no longer considered a major pest. Eventually, these pesticides were proven harmful to people's health and the environment and as a result their use was prohibited. The absence and resistance to some of the pesticides combined with an increase in cross-continental travel has resulted in bed bug infestations increasing. The current methods which include human friendly pesticides, heat treatment and organics such as oils which the bugs find intolerable are not affective. Our novel approach uses Serratia marcescens, a member of the Enterobacteriaceae. It is reported as a highly efficient chitin degrader. We aim to use three chitinase genes obtained from S. marcescens in designing a chitin degrading E. coli. The bugs will be exposed to the E. coli via an artificial feeding device.