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Team:TecMonterrey
From 2013.igem.org
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By exploiting this inherent ability of E. coli, this project aims to combine 3 different approaches in one bacterial system: the development of an E. coli capable of producing two cancer-specific apoptosis inducing proteins, a secretion system for the delivery of therapeutic proteins, and the design of a control mechanism confining the production of the therapeutic proteins only in tumor-specific regions. | By exploiting this inherent ability of E. coli, this project aims to combine 3 different approaches in one bacterial system: the development of an E. coli capable of producing two cancer-specific apoptosis inducing proteins, a secretion system for the delivery of therapeutic proteins, and the design of a control mechanism confining the production of the therapeutic proteins only in tumor-specific regions. | ||
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Revision as of 02:44, 28 September 2013
Project descriptionIt has been shown that certain bacteria such as Escherichia coli, Salmonella, and Clostridium selectively colonize and grow in tumors and a number of reports have demonstrated that some bacteria are capable of targeting both primary tumors and metastases. By exploiting this inherent ability of E. coli, this project aims to combine 3 different approaches in one bacterial system: the development of an E. coli capable of producing two cancer-specific apoptosis inducing proteins, a secretion system for the delivery of therapeutic proteins, and the design of a control mechanism confining the production of the therapeutic proteins only in tumor-specific regions. | |
 iGEM TecMonterrey Team | |
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