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       <li>Our initial project was the full realization of the <i>E. calculus</i> strain. We even thought of selling the idea to TI ;-). However, we soon realized that the full realization would probably take (a little ;-)) longer than the three months devoted to the iGEM competition. Furthermore, we are also aware that integration of many independant biological modules is always more complicated than it seems. However, a first step toward integration is the demonstration that each biological module works individually as expected. We would then have good arguments in support of the <b>feasibility</b> of the whole project.

       <li>Interdisciplinarity is a pillar in Synthetic Biology. iGEM projects aim at modeling the biological reactions that were designed to promote a full integration of wet and dry lab experiments. Modeling the entire <i>E. calculus</i> system did not seem either feasible or even conceivable. We the focussed on only part of the project. In our whole <i> E. calculus</i> design, the diffusion of the carry was critical to implement the bacterial full adder. We then considered that modelling the diffusion of the carry molecule (AHL) was essential to fully support the feasibility of the design. Our results will provide interesting concepts that we hope will serve for similar design where diffusion of small molecules are necessary to achieve specific biological functions.  

<td><img style="width:20px;" src="https://static.igem.org/mediawiki/2013/c/c1/Icone-check-pink.png" class="imgcontenttableleft"/> Improve the function of an existing BioBrick Part or Device (created by another team or your own institution in a previous year), enter this information in the Registry </td>

Submit this new part to the iGEM Parts Registry (submissions must adhere to the iGEM Registry guidelines)</td>

<td style="border-top:1px solid #e5e6e6;"><img style="width:20px;" src="https://static.igem.org/mediawiki/2013/c/c1/Icone-check-pink.png" class="imgcontenttableleft"/> Help any registered iGEM team from another school or institution by, for example, characterizing a part, debugging a construct, or modeling or simulating their system</td>

<td style="border-top:1px solid #e5e6e6;"><img style="width:20px;" src="https://static.igem.org/mediawiki/2013/c/c1/Icone-check-pink.png" class="imgcontenttableleft"/> Your project may have implications for the environment, security, safety and ethics and/or ownership and sharing. Describe a novel approach that your team has used to help you and others consider these aspects of the design and outcomes of synthetic biology efforts.</td>

<td style="border-right:1px solid #e5e6e6; border-top:1px solid #e5e6e6;"><img style="width:20px;" src="https://static.igem.org/mediawiki/2013/c/c1/Icone-check-pink.png" class="imgcontenttableleft"/> Your project may have implications for the environment, security, safety and ethics and/or ownership and sharing. Describe one or more ways in which these or other broader implications have been taken into consideration in the design and execution of your project</td>

<td style="border-right:1px solid #e5e6e6; border-top:1px solid #e5e6e6;"><img style="width:20px;" src="https://static.igem.org/mediawiki/2013/c/c1/Icone-check-pink.png" class="imgcontenttableleft"/> Document at least one new standard BioBrick Part or Device used in your project/central to your project and submit this part to the iGEM Registry </td>