Team:Alberta/MainSafety

From 2013.igem.org

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  </head>
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  <body>
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    <div class="titlebar">
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<br>
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      <h3><font color="#A80000"><font size="6">The Littlest Mapmaker</font></font></h3>
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      <h4><i><font size="2">"Exploration into the world of <font color="#A80000">DNA Computing</font>"<br/>
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        Team Alberta: University of Alberta</font></i></h4>
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      <a href="http://www.ualberta.ca" class="ualberta-logo"><img src="/wiki/images/b/b3/Ualberta-logo.png" alt="University of Alberta"></img></a>
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      <a href="https://2013.igem.org" class="igem-logo"><img src="/wiki/images/a/ad/IGem-logo.png" alt="iGem Main Page"></img></a>
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    </div>
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    <div class="bin">
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      <ul class="navbar">
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        <li><a  href="/Team:Alberta">Home</a></li>
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        <li><a id="project" href="#">Project</a>
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          <ul>
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            <li><a href="/Team:Alberta/Background">Background</a></li>
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            <li><a href="/Team:Alberta/Overview">Overview</a></li>
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            <li><a href="/Team:Alberta/FutureDevelopment">Future Development</a></li>
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          </ul>
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        </li>
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        <li><a id="notebook" href="#">Notebook</a>
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          <ul>
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            <li><a href="/Team:Alberta/Results">Results</a></li>
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            <li><a href="/Team:Alberta/Protocols">Protocols</a></li>
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            <li><a href="/Team:Alberta/Parts">BioBricks</a></li>
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          </ul>
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        </li>
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        <li><a id="team" href="#">Team</a>
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          <ul>
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            <li><a href="/Team:Alberta/Team">Roster</a></li>
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            <li><a href="https://igem.org/Team.cgi?year=2013&team_name=Alberta">Official Profile</a></li>
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            <li><a href="/Team:Alberta/Attributions">Sponsors</a></li>
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          </ul>
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        </li>
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        <li><a id="humanpractices" href="#">Human Practices</a>
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          <ul>
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            <li><a href="/Team:Alberta/Outreach">Outreach</a></li>
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            <li><a href="/Team:Alberta/Community">Community</a></li>
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          </ul>
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        </li>
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        <li><i class="nav-icon"></i><a id="safety" href="#" class="active">Safety</a>
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          <ul>
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            <li><a href="/Team:Alberta/SafetyForm">Safety Form</a></li>
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            <li><a href="/Team:Alberta/FAQ">FAQ</a></li>
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            <li><a href="/Team:Alberta/Resources">Resources</a></li>
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          </ul>
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        </li>
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      <div class="igem-bar"><a href="https://2013.igem.org"><img src="/wiki/images/a/ad/IGem-logo.png"></img></a></div>
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        <p class="content-title">Where to start?</p>
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        <h3>Doesn’t <i>E. coli</i> cause food poisoning? If <i>E. coli</i> is so dangerous, why are they being used in labs?</h3>
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        <ul>
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          <li>Normal <i>E. coli</i> colonize the lower intestine of humans, while <b>producing Vitamin K</b> and
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            <b>protecting infection</b> from other harmful bacteria.</li>
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          <li>Only some strains of <i>E. coli</i> cause food poisoning, but our group is using a <b>harmless,
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            nonpathogenic strain</b>. This train is engineered to contain mutations that would not allow the <i>E.
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            coli</i> to survive outside the lab without particular nutrients.</li>
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          <li><i>E. coli</i> provides a well-studied and well-known <b>model system</b> to test and troubleshoot new
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            trials on.</li>
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        <p>Reference: <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1728375/">
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          http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1728375/</a></p>
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        <h3>What if plasmids containing <b>antibiotic resistance genes</b> were released into the environment despite
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          precautions?</h3>
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          <li>These genes are used in synthetic biology as selection tools.</li>
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          <li>There are lower chances of gene uptake by wild bacteria compared to lab-strain bacteria which
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            have perforated membranes.</li>
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          <li>In the case that wild bacteria did uptake the antibiotic resistance gene, that gene would
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            eventually be lost in the population without exposure to the antibiotic, because it is then a
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            disadvantage for the bacteria to carry the unused plasmids. (Evidence observed in past with the
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            decline of specific antibiotic resistance after the human population limited that antibiotic).</li>
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Latest revision as of 02:27, 29 October 2013