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Team:Evry/Modeling
From 2013.igem.org
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<p>The modeling part is planned around 4 main targets: | <p>The modeling part is planned around 4 main targets: | ||
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<p>For a better understanding of the bacteria our team is going to produce, we chose to first focus on the growth of an iron-chelating bacterial population.</p> | <p>For a better understanding of the bacteria our team is going to produce, we chose to first focus on the growth of an iron-chelating bacterial population.</p> | ||
<p>Let us suppose we have <math>N_0</math> initial siderophore-producing bacterias in a closed system with dissolved iron. Monitoring the evolution of those bacterias, the dissolved iron, the siderophores and the chelated iron through a simple model will help our biologists tune their constructions.</p> | <p>Let us suppose we have <math>N_0</math> initial siderophore-producing bacterias in a closed system with dissolved iron. Monitoring the evolution of those bacterias, the dissolved iron, the siderophores and the chelated iron through a simple model will help our biologists tune their constructions.</p> | ||
Revision as of 14:24, 25 July 2013
Modeling overview
The modeling part is planned around 4 main targets:
- Growth of an iron-chelating bacterial population
- Risk assessment : forecast, control, auto-regulation, ...
- Bacterial activity : iron-chelation rate, avidity (cellular scale)
- Intestine mapping and interactions
First approach
For a better understanding of the bacteria our team is going to produce, we chose to first focus on the growth of an iron-chelating bacterial population.
Let us suppose we have initial siderophore-producing bacterias in a closed system with dissolved iron. Monitoring the evolution of those bacterias, the dissolved iron, the siderophores and the chelated iron through a simple model will help our biologists tune their constructions.
