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Team:Ciencias-UNAM
From 2013.igem.org
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<div id="u54" class="u54" > | <div id="u54" class="u54" > | ||
| - | <div id="u54_rtf"><p | + | <div id="u54_rtf"><p align="justify"><span style="font-family:Arial;font-size:13px;font-weight:normal;font-style:normal;text-decoration:none;color:#666666;">This year's project is an <i>In vivo</i> production of an antimicrobial peptide regulated by <i>quorum sensing</i>. We designed a synthetic system in <i>E. coli</i> to express an antimicrobial peptide (Cathelicidin LL-37) <i>in vivo</i> only in the presence of a quorum sensing molecule (AI-2) and expel it with an efflux pump in order to act against targeted gastrointestinal pathogens.</span></p></div> |
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<div id="u55" class="u55" > | <div id="u55" class="u55" > | ||
| - | <div id="u55_rtf"><p | + | <div id="u55_rtf"><p align="justify"><span style="font-family:Arial;font-size:13px;font-weight:normal;font-style:normal;text-decoration:none;color:#666666;">We are the team from Facultad de Ciencias, UNAM in Mexico City. Our team brings together students and teachers from all over the country, with various backgrounds and interests.</span></p></div> |
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<div id="u56" class="u56" > | <div id="u56" class="u56" > | ||
| - | <div id="u56_rtf"><p | + | <div id="u56_rtf"><p align="justify"><span style="font-family:Arial;font-size:13px;font-weight:normal;font-style:normal;text-decoration:none;color:#666666;">We submitted several devices mainly to test and use the following parts:<br><b>Cathelicidin LL-37:</b> An antimicrobial peptide against bacterial infection.<br> <b>MarA:</b> A peptide responsible for an efflux pump in <i>E. coli</i> that is related to its resistance to cathelicidin and similar peptides.</span></p></div> |
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| - | <div id="u57_rtf"><p | + | <div id="u57_rtf"><p align="justify"><span style="font-family:Arial;font-size:13px;font-weight:normal;font-style:normal;text-decoration:none;color:#666666;">The project we developed this year yielded several results. We achieved to characterise and contribute to the iGEM Registry. In this section we present what we think we are our best and main results.</span></p></div> |
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| - | <div id="u58_rtf"><p | + | <div id="u58_rtf"><p align="justify"><span style="font-family:Arial;font-size:13px;font-weight:bold;font-style:normal;text-decoration:none;color:#666666;">Read the abstract</span></p></div> |
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| - | <div id="u59_rtf"><p | + | <div id="u59_rtf"><p align="justify;"><span style="font-family:Arial;font-size:13px;font-weight:bold;font-style:normal;text-decoration:none;color:#666666;">Meet the team</span></p></div> |
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Latest revision as of 04:20, 28 September 2013
HOME
PROJECT
HUMAN PRACTICES
TEAM
SAFETY
Overview
General Design
Wet Lab
Dry Lab
Conclusions
References
Bios
Sponsors
Overview
Journalism
Interviews
THE PROJECT
THE PEOPLE
PARTS
ACHIEVEMENTS
This year's project is an In vivo production of an antimicrobial peptide regulated by quorum sensing. We designed a synthetic system in E. coli to express an antimicrobial peptide (Cathelicidin LL-37) in vivo only in the presence of a quorum sensing molecule (AI-2) and expel it with an efflux pump in order to act against targeted gastrointestinal pathogens.
We are the team from Facultad de Ciencias, UNAM in Mexico City. Our team brings together students and teachers from all over the country, with various backgrounds and interests.
We submitted several devices mainly to test and use the following parts:
Cathelicidin LL-37: An antimicrobial peptide against bacterial infection.
MarA: A peptide responsible for an efflux pump in E. coli that is related to its resistance to cathelicidin and similar peptides.
The project we developed this year yielded several results. We achieved to characterise and contribute to the iGEM Registry. In this section we present what we think we are our best and main results.
Read the abstract
Meet the team
Read more...
Read more...
Gallery
