Team:SYSU-Software

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<h1 class="h">CAST </h1>
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<h3 class="h">Designer</h3>
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<span>Computer Aided Synbio Tool-<br/>An Integrated Tool for Synthetic Biology</span>
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<!-- <p>Synthetic Biology, depending on interdisciplinary knowledge and experience, cooperates wet and dry experiments to engineer the artificial biological systems. Here, our team has developed an integrated tool, <b>CAST (Computer Aided Synbio Tool)</b>, to address specific technical challenges in synthetic biology. Our software can automatically perform the regulatory networks and gene circuits designing with Biobricks and other regulatory elements, modeling, vector designing and proposal build. User can also optimize or alter the default methods to fulfill some further demands. All of the designed elements, networks and vectors can be stored in database to be shared through CAST. In addition, we incorporated <a href="https://2013.igem.org/Team:SYSU-Software/wetlab"><b>wetlab experimentation</b></a> into our project to validate our <a href="https://2013.igem.org/Team:SYSU-Software/model"><b>new simulation model</b></a> that work with standard dynamic characteristic. Altogether, <b>the combination of the <font color="#ff0000">design automation</font>, <font color="#ff0000">innovative models and algorithms</font>, and <font color="#ff0000">wetlab validation</font> makes complex biological systems accessible to researchers who want rapid, intuitive, and high-quality accomplish their designs</b>. -->
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<p>Synthetic Biology, depending on interdisciplinary knowledge and experience, cooperates wet and dry experiments to engineer the artificial biological systems. Our team has developed an integrated tool, <b>CAST (Computer Aided Synbio Tool)</b>, to address specific technical challenges in synthetic biology. Our software can automatically perform the regulatory networks and gene circuits designing, modeling, vector designing and proposal build.All of the design can be stored in database to be shared through CAST. In addition, we incorporated <a href="https://2013.igem.org/Team:SYSU-Software/wetlab"><b>wetlab experimentation</b></a> into our project to validate our <a href="https://2013.igem.org/Team:SYSU-Software/model"><b>new simulation model</b></a> that work with standard dynamic characteristic. Altogether, <b>the combination of the <font>design automation</font>, <font>innovative models and algorithms</font>, and <font>wetlab validation</font> makes complex biological systems accessible to researchers who want rapid, intuitive, and high-quality accomplish their designs.</b>
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<h2>Introduction</h2>
 
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<span>Accurate simulation and gene circuit design are essential but difficult parts in synthetic biology.Here, we designed CAST to cover the workflow from beginning to end, users can focus on function design and the gene circuit would be automatically designed. Furthermore, we developed a new simulation model that work with standard dynamic characteristic and verified by wetlab experiments. Moreover, we build an expandable database that users can contribute their own dynamic information which would lead to more accurate and sufficient dynamic information of all the Biobricks. Finally, our software is designed as an easy deployed server so that it can be used on personal purpose or shared by a whole lab or institution.
 
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Sun Yat-Sen University, Guangzhou, China
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Sun Yat-Sen University, Guangzhou, China<br/>
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<h2>ADDRESS</h2>
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135# Xingang Rd.(W.), Haizhu Guangzhou, P.R.China
135# Xingang Rd.(W.), Haizhu Guangzhou, P.R.China
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Latest revision as of 08:35, 3 June 2014

Team:SYSU-Software