Team:Freiburg/main2

From 2013.igem.org

(Difference between revisions)

Latest revision as of 16:38, 27 September 2013

Abstract

Our Team developed a universal toolkit, termed uniCAS, that enables customizable gene regulation in mammalian cells. Therefore, we engineered the recently discovered and highly promising CRISPR/Cas9 system. The regulation is based on the RNA-guided Cas9 protein, which allows targeting of specific DNA sequences. Our toolkit comprises not only a standardized Cas9 protein, but also different effector domains for efficient gene activation or repression.

Our Project

Activation
Repression
Epigenetics

Multiple targeting
uniBAss
Light switch

Highlights

Toolkit

Use our Toolkit to regulate your genes!

HP

Our Team developed...

Team

Our Team developed...

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 #table_viereck tr td ul li img{
-height:50px;
+height:60px;
-}
-#cas{
-height:150px;
-float:left;
-margin-top:50px;
-z-index:1;
 }
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 }
-#activation{
-height:50px;
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-}
-#epigenetic{
-height:50px;
-margin-top:60px;
-margin-left:5px;
-}
-#multiple_targeting{
-height:50px;
-margin-top:70px;
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-}
-#licht{
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-margin-top:70px;
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-}
 #text_gross{
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 color:white;
 width:500px;
+height:300px;
 padding-top:5px;
 font-family:Arial;
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 float:left;
 background: url(https://static.igem.org/mediawiki/2013/9/94/Freiburg_2013_main2_Cas.png);
-background-size: 200px;
+background-size: 250px;
-background-position:center;
+background-position:120px 150px;
+background-repeat: no-repeat;
+}
+#text-box2 ul li span{
+font-size: 20px;
+font-family:'Yanone';
 }
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 }
-#icon_left{
-float: left;
-}
-#icon_right{
-float: left;
-}
-#icon_left span{
-color:white;
-font-size: 15px;
-padding-top:32px;
-}
-#icon_right span{
-color:white;
-font-size: 15px;
-padding-top:32px;
-}
-#icon_left img{
-height:50px;
-}
-#icon_right img{
-height:50px;
-}
 @font-face {
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    <div>
-<div style="z-index:2;">
+<ul style="margin-left:40px;">
-<ul>
-<li>
+<li style="margin-top:-30px;">
 <span> Activation </span>
-<img  src="https://static.igem.org/mediawiki/2013/0/03/Freiburg_2013_main2_Activation.png" >
+<img  src="https://static.igem.org/mediawiki/2013/0/03/Freiburg_2013_main2_Activation.png">
 </li>
-<li>
+<li style="margin-left: -40px;">
 <span> Repression </span>
 <img  src="https://static.igem.org/mediawiki/2013/e/e7/Repression_freiburg_13.png">
 </li>
-<li>
+<li style="margin-bottom:-30px;">
 <span> Epigenetics </span>
 <img src="https://static.igem.org/mediawiki/2013/3/31/Freiburg_2013_main2_Epigenetic.png">
 </li>
 </ul>
-</div>
-<!--
-<div style="z-index:1;">
-<img id="cas" src="https://static.igem.org/mediawiki/2013/9/94/Freiburg_2013_main2_Cas.png">
-</div>
--->
-<div style="z-index:2;">
-<ul>
-<li>
-  <img src="https://static.igem.org/mediawiki/2013/e/ef/UniBAss_freiburg_13.png">
-<span> uniBAss</span>
-</lI>
-<li>
+<ul style="margin-left:130px;">
+<li style="margin-top: -30px;">
    <img src="https://static.igem.org/mediawiki/2013/b/bb/Freiburg_2013_main2_Multiple_Targeting.png">
 <span> Multiple targeting </span>
 </li>
-<li>
+<li style="margin-left: 40px;">
+  <img src="https://static.igem.org/mediawiki/2013/e/ef/UniBAss_freiburg_13.png">
+<span> uniBAss</span>
+</lI>
+<li style="margin-bottom:-30px;">
    <img src="https://static.igem.org/mediawiki/2013/9/9a/Freiburg_2013_main2_Licht.png">
 <span> Light switch </span>
 </li>
 </ul>
-</div>
 </div>