Team:Glendale Community College

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Welcome to our website.
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<b><p style="color:red;margin-left:20px;">This wiki is still under construction.</p></b>
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!align="center"|[[Team:Glendale_CC_AZ|Home]]
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!align="center"|[[Team:Glendale_CC_AZ/Team|Team]]
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!align="center"|[https://igem.org/Team.cgi?year=2013&team_name=Glendale_CC_AZ Official Team Profile]
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!align="center"|[[Team:Glendale_CC_AZ/Project|Project]]
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!align="center"|[[Team:Glendale_CC_AZ/Parts|Parts Submitted to the Registry]]
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!align="center"|[[Team:Glendale_CC_AZ/Modeling|Modeling]]
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!align="center"|[[Team:Glendale_CC_AZ/Notebook|Notebook]]
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!align="center"|[[Team:Glendale_CC_AZ/Safety|Safety]]
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!align="center"|[[Team:Glendale_CC_AZ/Attributions|Attributions]]
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== '''Introduction''' ==
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In the past other teams (Osaka, University College London) have explored the resistance genes in the bacteria D. radiodurans. These resistance genes convey resilience against high levels of radiation, oxidative stress and desiccation in that the DNA repairs itself when damaged from these stressors. The interesting thing about these stressors is that the DNA repairs itself in the same way regardless of the type of stress. Simply put, the system responds to DNA damage and makes the necessary repairs. From here, the project first aims to provide extra validation data to those studies. Additionally the ultimate purpose of this iGEM project is to explore the resistance genes in a similar bacteria, Deinococcus hopiensis, as a novel source of these genes within the Deinococcus genus. For this purpose the project then uses the genes to transform a desiccation, radiation, and oxidative stress sensitive bacteria, E. coli to improve the robustness of the cells against the particular stressors of desiccation and oxidative stress.
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== Why not radiation? ==
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Safety clearance of the team does not warrant using high levels of radiation. Desiccation and oxidative stress were determined to be safely measurable stressors.
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==What applications can this have for real life? ==
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Desiccation resistance is a major problem in Arizona agriculture. Being able to use these genes possibly in plants may improve agriculture within the desert areas of the Southwest, Africa, and the Middle East. This could help ease the problems of world hunger if food crops are able to grow easier in arid climates. Additionally, radiation resistance is very important for space travel. Papers have been published talking about using the resistance genes in D. radiodurans for space travel and that way plants could be more easily grown in space travel.
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==Why using materials from other teams? ==
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Firstly, in science, adding validation data is always a very important and welcome resource. In addition to the validation data, the main goal of the project is to look for these same genes in a sister bacteria and see if those genes convey the same resistance.
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== '''Where we're from''' ==
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== '''Glendale Community College''' ==
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[[File:Glendale CC AZ logo.png]]
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<p>Hello.</p>
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    <h4>Glendale Community College Arizona<a href="http://www2.gccaz.edu"><img
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    <p><big style="color: rgb(32,178,170);"><big><big><big> iGEM 2013</big></big></big></big></p>
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    <p><b><big style="color: rgb(95,158,160);"><big><big><big> Desiccation Toolkit</big></big></big></big></b></p>
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    <p>Desert areas, making up almost one-quarter of the Earth surface, are home to 500 million people. As a result of human habitation, every continent in the world except Antarctica is increasingly and adversely affected by desertification. Studies forecasting climate trends indicate that desert regions will face an even drier future – in regard to both climatic factors and drought conditions – stemming from the influence of human activities. One human-created impact on these desert environments is pollution. Many remediation challenges exist specific to the extremely dry conditions present in these arid locales. For example, what happens when a desert area is polluted with such substances as plastics, where commonly employed bioremediation agents used for environmental cleanup cannot survive desert climates’ high temperature and low humidity extremes? Our team has developed a kit containing biological components that will provide desiccation resistance to organisms used to facilitate the elimination of contaminants, like plastics, in desert-like environments. Our goal is to design an assortment of complementary parts, which will strengthen organisms and help to broaden their climatic and geographic range of effectiveness. While some parts included in our kit could, conceivably, provide resistance to other types of stresses, such as ionizing radiation, we will initially focus on desiccation. Because of its potential to expand the extent of the efficacy of these biological breakdown expedients into even climatically extreme territories, our kit could be a valuable addition to any bioremediation project.</p>
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    <h3 style="text-align: center;">Welcome to Our Wiki!</h3>
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    <p style="text-align: center;">Some pictures of our
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    experiments.</p>
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Latest revision as of 02:33, 28 September 2013

Glendale Community College ArizonaGCC

iGEM

iGEM 2013

Desiccation Toolkit

Desert areas, making up almost one-quarter of the Earth surface, are home to 500 million people. As a result of human habitation, every continent in the world except Antarctica is increasingly and adversely affected by desertification. Studies forecasting climate trends indicate that desert regions will face an even drier future – in regard to both climatic factors and drought conditions – stemming from the influence of human activities. One human-created impact on these desert environments is pollution. Many remediation challenges exist specific to the extremely dry conditions present in these arid locales. For example, what happens when a desert area is polluted with such substances as plastics, where commonly employed bioremediation agents used for environmental cleanup cannot survive desert climates’ high temperature and low humidity extremes? Our team has developed a kit containing biological components that will provide desiccation resistance to organisms used to facilitate the elimination of contaminants, like plastics, in desert-like environments. Our goal is to design an assortment of complementary parts, which will strengthen organisms and help to broaden their climatic and geographic range of effectiveness. While some parts included in our kit could, conceivably, provide resistance to other types of stresses, such as ionizing radiation, we will initially focus on desiccation. Because of its potential to expand the extent of the efficacy of these biological breakdown expedients into even climatically extreme territories, our kit could be a valuable addition to any bioremediation project.

Welcome to Our Wiki!

Some pictures of our experiments.

Retrieved from "http://2013.igem.org/Team:Glendale_Community_College"