Team:Virginia/Human Practices Overview

From 2013.igem.org

(Difference between revisions)
 
(22 intermediate revisions not shown)
Line 190: Line 190:
#menu11 ul li:hover span.text a{
#menu11 ul li:hover span.text a{
     text-decoration:none;
     text-decoration:none;
-
color:#2B60DE;
+
color:#66CCFF;
 +
}
 +
#btext span {
 +
padding-top:30px;
 +
}
 +
#groupbio span {
 +
font-size:20px;
 +
text-decoration:underline;
 +
padding-top:50px;
 +
}
 +
#btext p a{
 +
text-decoration:none;
 +
color:#66ccff;
}
}
</style>
</style>
Line 219: Line 231:
                 <p><a href="https://2013.igem.org/Team:Virginia/Results">Results</a></p>
                 <p><a href="https://2013.igem.org/Team:Virginia/Results">Results</a></p>
                 <p><a href="https://2013.igem.org/Team:Virginia/Modeling">Modeling</a></p>
                 <p><a href="https://2013.igem.org/Team:Virginia/Modeling">Modeling</a></p>
-
                 <p><a href="https://2013.igem.org/Team:Virginia/Applications">Applications</a></p></span>
+
                 <p><a href="https://2013.igem.org/Team:Virginia/Software">Software</a></p>
 +
 
 +
                <p><a href="https://2013.igem.org/Team:Virginia/Chassis_Improvements">Chassis Improvements</a></p></span>
         </li>
         </li>
         <li>
         <li>
Line 233: Line 247:
                 <span class="text">
                 <span class="text">
                 <p><a href="https://2013.igem.org/Team:Virginia/Human_Practices_Overview">Overview</a></p>
                 <p><a href="https://2013.igem.org/Team:Virginia/Human_Practices_Overview">Overview</a></p>
-
                 <p><a href="https://2013.igem.org/Team:Virginia/Public_Perception">Public Perception</a></p>
+
                 <p><a href="https://2013.igem.org/Team:Virginia/Safety Considerations">Safety Considerations</a></p>
-
                 <p><a href="https://2013.igem.org/Team:Virginia/Relevance">Relevance</a></p>
+
                 <p><a href="https://2013.igem.org/Team:Virginia/High_School_Education_Series">High School Education Series</a></p>
-
          <p><a href="https://2013.igem.org/Team:Virginia/Outreach">Outreach</a></p></span>
+
                <p><a href="https://2013.igem.org/Team:Virginia/Documentary">Documentary</a></p>
 +
                <p><a href="https://2013.igem.org/Team:Virginia/Media_Coverage">Media Coverage</a></p></span>
         </li>
         </li>
         <li>
         <li>
Line 248: Line 263:
<div id="groupbio">
<div id="groupbio">
<div id="btext">
<div id="btext">
-
<p> <p style="text-indent: 5em;">Even a miracle drug that cures all cancers, bacteria that clear plaque from coronary arteries and viruses that amend errors in the human genome mean nothing if they cannot be administered in a safe and non-toxic manner. Because of this concern, it is imperative for ambitious synthetic biologists and IGEM teams to first address this issue of safety. Many promising treatments fall short when put to the test in vivo due to one or more issues with any of the following: toxicity, poor pharmacokinetics and ineffective delivery. For these reasons, there is a significant need for versatile delivery vehicles capable of carrying therapies to select targets while minimizing adverse side effects. Such vectors could render those common hindrances inconsequential, offering new hope to a myriad of abandoned drugs and improving the efficacy of future ones.  </p>
+
<span><u>Human Practices Overview</u></span>
 +
<br>
 +
<p> <p style="text-indent: 5em;">As synthetic biologists engineering intricate systems, we often forget to consider the larger bioethical implications of our work. Meanwhile, the public focuses on these implications rather than the science, leading to widespread concern. As has been shown by the recent controversy surrounding GMO-based products, even the most beneficial research cannot be implemented without public approval; additionally, such research might not even be conducted in the first place should it lose funding from taxpayer dollars through the NIH. </p>
 +
<p> <p style="text-indent: 5em;">Given these considerations, we were alarmed to learn that only 18% of Americans believe that the benefits of synthetic biology outweigh the risks (Awareness & Impressions of Synthetic Biology, Woodrow Wilson International Center for Scholars). To combat this problem, we developed a dual-focus, comprehensive educational program targeting both students and adults. Educating high school students through a standardized curriculum and informing adults through a brief documentary, we hope to increase both public knowledge and acceptance of synthetic biology. Additionally, multiple features of the team in the media have broadcasted iGEM and synthetic biology to the public at large. </p>
 +
 
 +
<br><br>
 +
<p>For most detailed information regarding our human practices efforts, please see the links to the following under our human practices menu:</p>
 +
 
 +
<p> <p style="text-indent: 5em;"> <u><a href="https://2013.igem.org/Team:Virginia/Safety_Considerations">Safety Considerations</a></u> – In consultation with the UVA Environmental Health & Safety Department, appropriate laboratory precautions were taken according to biosafety standards. Please view our basic safety form and part two biosafety forms for human serum and Yersinia enterocolitica, as are available on this link. </p>
 +
 
 +
<p> <p style="text-indent: 5em;"> <u><a href="https://2013.igem.org/Team:Virginia/High_School_Education_Series">High School Education Series</a></u> Through partnership with Renaissance High School in downtown Charlottesville, VA, we developed a comprehensive 6-workshop curriculum to expose high school students to synthetic biology. Entirely standardized, this curriculum may be easily adapted by any collegiate iGEM team to instruct and develop a high school iGEM team. Links to all course materials, including a syllabus, instructor notes, PowerPoint presentations, interactive activities, recommended readings, and discussion questions, are available.  </p>
 +
 
 +
<p> <p style="text-indent: 5em;"> <u><a href="https://2013.igem.org/Team:Virginia/Documentary">Documentary</a></u> – Footage from interviews with three experts in biology, medicine, and bioethics were compiled within a short documentary to explore topics in biosafety, open source research, and the potential impact of our specific minicell project. Although embedded within our wiki, the documentary is also available on YouTube to effectively reach a wide audience. </p>
 +
 
 +
<p> <p style="text-indent: 5em;"><u><a href="https://2013.igem.org/Team:Virginia/Media_Coverage">Media Coverage</a></u> – Featured in multiple media outlets, including CVille Weekly, the Daily Progress, UVA Today, NBC 29, and WUVA, we are not only bringing synthetic biology to the public through our high school education series and documentary, but through the press as well.  </p>
-
<p><p style="text-indent: 5em;">This year, Team Virginia sought to develop a safe and modular E. coli delivery-chassis that could be easily incorporated into a variety of other projects, making the many advantages listed above widely available. Our initial investigation led us to a forgotten discovery from the 1950’s—the bacterial minicell. Originally looked into for their potential as safer vaccines, minicell research dwindled over time due to lagging microbiological and genetic technology. While largely neglected for decades, minicells are only now resurfacing, in the wake of the recent, explosive growth of the modern biotechnology industry. As an intermediate between artificially constructed liposomes and live bacteria,a minicell captures the best qualities of both existing platforms, while lacking many of their worst features. Without a doubt, minicells are poised to become a game-changing vehicle for novel therapies.</p>
 
  </div></div></div>
  </div></div></div>

Latest revision as of 01:57, 29 October 2013

VGEM Welcomes You!

Human Practices Overview

As synthetic biologists engineering intricate systems, we often forget to consider the larger bioethical implications of our work. Meanwhile, the public focuses on these implications rather than the science, leading to widespread concern. As has been shown by the recent controversy surrounding GMO-based products, even the most beneficial research cannot be implemented without public approval; additionally, such research might not even be conducted in the first place should it lose funding from taxpayer dollars through the NIH.

Given these considerations, we were alarmed to learn that only 18% of Americans believe that the benefits of synthetic biology outweigh the risks (Awareness & Impressions of Synthetic Biology, Woodrow Wilson International Center for Scholars). To combat this problem, we developed a dual-focus, comprehensive educational program targeting both students and adults. Educating high school students through a standardized curriculum and informing adults through a brief documentary, we hope to increase both public knowledge and acceptance of synthetic biology. Additionally, multiple features of the team in the media have broadcasted iGEM and synthetic biology to the public at large.



For most detailed information regarding our human practices efforts, please see the links to the following under our human practices menu:

Safety Considerations – In consultation with the UVA Environmental Health & Safety Department, appropriate laboratory precautions were taken according to biosafety standards. Please view our basic safety form and part two biosafety forms for human serum and Yersinia enterocolitica, as are available on this link.

High School Education Series Through partnership with Renaissance High School in downtown Charlottesville, VA, we developed a comprehensive 6-workshop curriculum to expose high school students to synthetic biology. Entirely standardized, this curriculum may be easily adapted by any collegiate iGEM team to instruct and develop a high school iGEM team. Links to all course materials, including a syllabus, instructor notes, PowerPoint presentations, interactive activities, recommended readings, and discussion questions, are available.

Documentary – Footage from interviews with three experts in biology, medicine, and bioethics were compiled within a short documentary to explore topics in biosafety, open source research, and the potential impact of our specific minicell project. Although embedded within our wiki, the documentary is also available on YouTube to effectively reach a wide audience.

Media Coverage – Featured in multiple media outlets, including CVille Weekly, the Daily Progress, UVA Today, NBC 29, and WUVA, we are not only bringing synthetic biology to the public through our high school education series and documentary, but through the press as well.