Team:Heidelberg/Project/Achievements

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                         <h1 style="float:left"><span style="font-size:150%;color:#333333;">Achievements.</span><span class="text-muted" style="font-size:85%"> Introducing NRPS to Synthetic Biology.</span></h1>
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                         <h1><span style="font-size:150%;color:#FFCC00;">iGEM Medals</span><span class="text-muted" style="font-size:90%"> for Non-Software Teams</span></h1>  
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<img src="https://static.igem.org/mediawiki/2013/7/74/Goldmedal.JPG.png" style="float:left; max-height:100px; margin-left:7%;">
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<center><img style="width:100%; margin-top:5%; margin-bottom:2%" src="https://static.igem.org/mediawiki/2013/d/d3/Heidelberg_achievements_Top.png" ></img></center>
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                            <div id="bronzemedal" class="medal" style="text-align: center";><h8><b>Bronze Medal </b> Requirements</h8>
 
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                                        <p>Team is registered!  <span class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;" data-trigger='click', data-title="iGEM Team Heidelberg", data-content='The Team Heidelberg is finally back in the iGEM competition this year. If you want to know more about our team visit our <a href="https://2013.igem.org/Team:Heidelberg/Team"><b>team-page</b></a>!'>
 
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                                        </p> </span>
 
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                                        <p> Judging form is completed and submitted!  <span href="#" class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;" data-trigger='click', data-title="Judging form", data-content='Our <a href="https://igem.org/2013_Judging_Form?id=1152"><b>judging form</b></a> was filled in and is available online.'> </p></span>
 
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                                        <p> Project description of the Philosopher's Stone online! <span href="#" class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;" data-trigger='click', data-title="Project description", data-content='Our project description is available on the <a href="https://2013.igem.org/Team:Heidelberg/Project"><b>Project website</b> </a> were you can also get a basic overview. '>
 
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                                        </p></span>
 
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                                        <p> Poster is prepared for the European Jamboree in Lyon!  <span href="#" class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right"style="font-size: 11px;" data-trigger='click', data-title="Poster presentation at European jamboree", data-content='We are looking forward to see you at the poster presentation!'>
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                  <div class="bronzebox" >
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<a class="fancybox fancyGraphical" href="https://static.igem.org/mediawiki/2013/3/3e/Heidelberg_Achievements_sidebar.png">
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                                        <p> New standard BioBrick is documented! <span href="#" class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;" data-trigger='click', data-title="New standard Biobrick", data-content='We submitted 20 BioBricks which are summerized in an table on <a href="https://2013.igem.org/Team:Heidelberg/Parts"><b>submitted parts.</b></a> Feel also free to browse the parts we offer the community for example <a href="http://parts.igem.org/Part:BBa_K1152013?title=Part:BBa_K1152013"><b>BBa_K1152013</b></a>'>
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    <img style="width:100%; margin-top:2%; padding:1%;border-style:solid;border-width:0px;border-radius: 5px;" src="https://static.igem.org/mediawiki/2013/3/3e/Heidelberg_Achievements_sidebar.png" ></img>
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                                <div class="col-md-10 jumbotron" style="background-image:url(https://static.igem.org/mediawiki/2013/6/68/Heidelberg_Achievements_Haken2.png); background-size:100%; font-size:14px">
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Automated Design of <b>Custom Non-Ribosomal Peptide Synthetases</b>
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<br><br><br>
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Production of <b><a href="https://2013.igem.org/Team:Heidelberg/Project/Tyrocidine">Synthetic Peptides</a></b> in different engineered <em>E. coli</em> Hosts
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<br><br><br>
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Invention of a <a href="https://2013.igem.org/Team:Heidelberg/Project/Indigoidine-Tag">Universal Tag</a></b> for Non-Ribosomal Peptide labeling <em>in vivo</em>
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<br>
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Using the <a href="https://2013.igem.org/Team:Heidelberg/Project/Indigoidine-Tag">Tag</a> for <b>peptide characterization and quantification of production</b>
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<br><br><br>
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Application of <a href="https://2013.igem.org/Team:Heidelberg/Project/Delftibactin">delftibactin NRP</a> for <b>sustainable Gold Recycling</b>
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<br><br><br>
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Introducing our standardized Framework for Production of Synthetic Peptides to the Synbio Community: <b><a href="https://2013.igem.org/Team:Heidelberg/RFCs">RFC 99 and RFC 100</a></b>
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<br>
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<b>Having lots of <a href="<a href="https://2013.igem.org/Team:Heidelberg/Team/Gallery">fun</a> and very much looking forward to the Jamboree in Boston</b>
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<br><br>
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                            <div class="col-sm-3">
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                  </div>
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                                <div id="silvermedal" class="medal" style="text-align: center";><h8><b>Silver Medal </b> Requirements
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</h8><br/>
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                    <div class="silverbox" style="margin-top:10%">
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                    <p> New BioBricks are characterized! <span  href="#" class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px; "data-trigger="click"  data-title="New characterized Biobricks"  data-placement="bottom" data-content="We characterized our new BioBricks experimentally and documented our findings in the parts registry: for example: <a href="http://parts.igem.org/Part:BBa_K1152006?title=Part:BBa_K1152006"><b>BBa_K1152006</b></a>"></p></span><br/>
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                    <p> New BioBricks are submitted! <span href="#" class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;" data-trigger="click" data-placement="bottom"  data-title="New submitted Biobricks" data-content='We submitted <a href="https://2013.igem.org/Team:Heidelberg/Parts"><b>20 parts</b></a> to the parts registry - ranging from the basis for a NRPS-module library, to novel NRPSs and constructs, where entirely synthetic protein-domains were introduced.  '></p></span><br/>
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                        <h1 style="float:left"><span style="font-size:150%;color:#333333;">Medal Requirements.</span><span class="text-muted" style="font-size:85%"> Aiming for Gold.</span></h1>
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<img src="https://static.igem.org/mediawiki/2013/7/74/Goldmedal.JPG.png" style="float:left; max-height:100px; margin-left:7%;">
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                    <p> Implications for ethics are pointed out! <span href="#" class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;" data-trigger="click" data-title="Project`s implications" data-placement="bottom" data-content="At the beginning of the project, we pointed out possible ethical implications in an essay. You can read this essay here: <a href="https://2013.igem.org/Team:Heidelberg/Ethics"><b>Essay!</b></a> "></p></span>
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    <div class="row" style="display:table-row;">
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        <div id="best" class="medal">
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            <h8><b>Best New Standard</b></h8>
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                <div class="requirement">
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                    <span class="requirement">We submitted RFC99 and RFC100!</span>
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                    <span  class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;;" data-title="New standard - RFC" data-placement="right" data-content='We developed a standardized framework for the production of synthetic peptides based on engineered NRPSs. Our framework is documented in &lt;a href="/Team:Heidelberg/RFCs#rfc99"  target="_blank"&gt;&lt;b&gt;RFC 99&lt;/b&gt;&lt;/a&gt; and &lt;a href="/Team:Heidelberg/RFCs" &gt;&lt;b&gt;RFC 100&lt;/b&gt;&lt;/a&gt;!'></span>
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                <a href="/Team:Heidelberg/RFCs#rfc99"><span class="highlight_button" style="background-image: url('https://static.igem.org/mediawiki/2013/0/01/Heidelberg_bn_round_rfc99.png');"></span></a>
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                <a href="/Team:Heidelberg/RFCs"><span class="highlight_button" style="background-image: url('https://static.igem.org/mediawiki/2013/7/7f/Heidelberg_bn_round_rfc100.png');"></span></a>
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         <div id="parts" class="medal">
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            <h8 ><b>Parts!</b></h8>
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                     <span class="requirement">Have a look on our different parts!</span>
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            <div id="goldmedal" class="medal" style="text-align:center" ><h8><b>Gold Medal </b> Requirements</h8><br/>
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                    <span  class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;" data-trigger='click' data-placement="bottom" data-title="Bringing Non-Ribosomal Peptide Synthesis to iGEM- our Parts" data-content='&lt;a href="https://2013.igem.org/Team:Heidelberg/Parts"&gt;&lt;b&gt;Visit our parts page!&lt;/b&gt;&lt;/a&gt;'></span>
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                     <p> Functions of existing BioBricks were improved! <span   href="#" class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;" data-trigger="click" data-title="Improved BioBricks" data-placement="left" data-content="Functions of three existing BioBricks were improved: <br/> <br/> 1) We annotated the PPTase on [Part, link zur registry]. By submitting additional PPTases to the parts registry, we expanded apllications of PPTases. <br/> <br/> 2) We identified a missing sequence in the backbone pSB4K5 from the spring distribution of 2012. <br/><br/> 3) We further characterized the toxicity of [Part, link zur registry], an exporter in <i>E. coli</i>."></p> </span><br/>
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        <div id="attribution" class="medal">
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            <h8><b>Attribution and Contribution!</b></h8>
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                    <p> We helped other iGEM teams! <span  href="#" class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;" data-trigger="click" data-title="Collaboration" data-placement="left", data-content="In the past months, we collaborated with other student iGEM teams: We sent Freiburg a eukaryotic cell line. Norwich received soil samples from the beautiful forests of Heidelberg and we helped Purdue by participating in their survey. Additionally, we fixed a bug in Cambridge's Gibthon software tool. The parts registry is now properly connected to Gibthon and importing parts directly from the registry is possible (if they accept our pull request on GitHub)."></p> </span><br/>
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            <div>
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                <div class="requirement">
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                    <p> Novel approach to ownership and sharing is described!<span class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;" data-trigger="click" data-title="NRPS-Designer" data-placement="left"  data-content="With the NRPS Designer we share with the iGEM community is a novel approach to ownership and sharing in synthetic biology. Visit our NRPS Designer and try it yourself."></p> </span> <br/><br/><br/><br/><br/><br/><br/><br/><br/><br/>
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                    <span class="requirement">Thank you for the great help!</span>
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</div>
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                    <span class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;" data-trigger='click' data-placement="left" data-title="Attributions, Sponsors and Acknowledgements"  data-content='We thank our &lt;a href="https://2013.igem.org/Team:Heidelberg/Sponsors"&gt;&lt;b&gt; sponsors&lt;/b&gt;&lt;/a&gt;, &lt;a href="https://2013.igem.org/Team:Heidelberg/Team/Acknoledgements"&gt;&lt;b&gt;all people&lt;/b&gt;&lt;/a&gt; that kindly shared their laboratory equipment and constructs with us and &lt;a href="https://2013.igem.org/Team:Heidelberg/AttributionsII"&gt;&lt;b&gt;attribute&lt;/b&gt;&lt;/a&gt; the work of our team!'></span>
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                <div id="best" class="medal"><h8><b>Best New Standard</b></h8>
 
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            <p>  Improve the function of an existing BioBrick Part or Device <span  class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;margin-right:60%;" data-trigger="click" data-title="Non-ribosomal peptide synthetase" data-placement="right" data-content="Please explain briefly why you should receive any of these special prizes:"></p> </span>
 
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                <div id="parts" class="medal" ><h8 ><b>Parts!</b></h8>
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    <div class="row" style="margin-top:4%; display:table-row;">
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                 <p>Have a look on our different parts! <span class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;margin-right:60%;"data-trigger='click',data-placement="left", data-title="Non-ribosomal peptide synthetase", data-content='Link to our parts? '></p> </span>
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        <div id="bronzemedal" class="medal">
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            <h8><b>Bronze Medal</b> Requirements</h8>
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            <div>
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                 <div class="requirement">
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                    <span class="check"></span>
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                    <span class="requirement">Team is registered!</span>
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                    <span class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;" data-title="iGEM Team Heidelberg" data-content='The Team Heidelberg is finally back in the iGEM competition this year. If you want to know more about our team visit our &lt;a href="https://2013.igem.org/Team:Heidelberg/Team"&gt;&lt;b&gt;team-page&lt;/b&gt;&lt;/a&gt;!'></span>
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                </div>
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                <div class="requirement">
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                    <span class="check"></span>
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                    <span class="requirement">Judging form is completed and submitted!</span>
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                    <span class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;" data-title="Judging form" data-content='Our &lt;a href="https://igem.org/2013_Judging_Form?id=1152"&gt;&lt;b&gt;judging form&lt;/b&gt;&lt;/a&gt; was filled in and is available online.'></span>
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                <div class="requirement">
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                    <span class="check"></span>
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                    <span class="requirement">Project description of the Philosopher's Stone online!</span>
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                    <span class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;" data-title="Project description" data-content='Our project description is available on the &lt;a href="https://2013.igem.org/Team:Heidelberg/Project"&gt;&lt;b&gt;Project website&lt;/b&gt; &lt;/a&gt; were you can also get a basic overview.'></span>
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                </div>
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                <div class="requirement">
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                    <span class="check"></span>
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                    <span class="requirement">Poster is prepared for the European Jamboree in Lyon!</span>
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                    <span class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;" data-title="Poster presentation at European jamboree" data-content='Yupi! We won the prize for the best poster!!!'></span>
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                 </div>
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                <div class="requirement">
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                    <span class="check"></span>
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                    <span class="requirement">New standard BioBrick is documented!</span>
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                    <span class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;" data-title="New standard Biobrick" data-content='We submitted 20 BioBricks which are summarized on &lt;a href="https://2013.igem.org/Team:Heidelberg/Parts"&gt;&lt;b&gt;submitted parts.&lt;/b&gt;&lt;/a&gt; Feel also free to browse the parts we offer the community, for example &lt;a href="http://parts.igem.org/Part:BBa_K1152013?title=Part:BBa_K1152013"&gt;&lt;b&gt;BBa_K1152013&lt;/b&gt;&lt;/a&gt;'></span>
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            </div>
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        </div>
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        <div id="silvermedal" class="medal">
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            <h8><b>Silver Medal</b> Requirements</h8>
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            <div>
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                <div class="requirement">
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                    <span class="check"></span>
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                    <span class="requirement">New BioBricks are characterized!</span>
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                    <span class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;"  data-title="New characterized Biobricks"  data-placement="bottom" data-content='We characterized our new BioBricks experimentally and documented our findings in the parts registry: for example: &lt;a href="http://parts.igem.org/Part:BBa_K1152006?title=Part:BBa_K1152006"&gt;&lt;b&gt;BBa_K1152006&lt;/b&gt;&lt;/a&gt;'></span>
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                </div>
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                <div class="requirement">
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                    <span class="check"></span>
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                    <span class="requirement">New BioBricks are submitted!</span>
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                    <span class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;" data-placement="bottom"  data-title="New submitted Biobricks" data-content='We submitted &lt;a href="https://2013.igem.org/Team:Heidelberg/Parts"&gt;&lt;b&gt;20 well characterized parts&lt;/b&gt;&lt;/a&gt; to the parts registry - ranging from the basic NRPS-modules and custom NRPSs producing peptides of choice to constructs for NRP tagging and NRPS constructs, where entirely synthetic NRPS-domains were introduced.'></span>
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                </div>
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                <div class="requirement">
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                    <span class="check"></span>
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                    <span class="requirement">Implications for ethics are pointed out!</span>
 +
                    <span class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;" data-title="Project's implications" data-placement="bottom" data-content='At the beginning of the project, we pointed out possible ethical implications in an essay. You can read this essay here: &lt;a href="https://2013.igem.org/Team:Heidelberg/Ethics"&gt;&lt;b&gt;Essay!&lt;/b&gt;&lt;/a&gt;'></span>
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            <div id="goldmedal" class="medal">
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            <h8><b>Gold Medal</b> Requirements</h8>
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            <div>
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                <div class="requirement">
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                    <span class="check"></span>
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                    <span class="requirement">Functions of existing BioBrick was improved!</span>
 +
                    <span class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;" data-title="Improved BioBricks" data-placement="left" data-content='The function of the BioBricks &lt;a href="http://parts.igem.org/wiki/index.php?title=Part:BBa_K802006"&gt;&lt;b&gt;BBa_K802006&lt;b&gt;&lt;/a&gt; and &lt;a href="http://parts.igem.org/Part:BBa_K302010"&gt;&lt;b&gt;BBa_K302010&lt;b&gt;&lt;/a&gt; were improved with our &lt;a href="http://parts.igem.org/Part:BBa_K1152009?title=Part:BBa_K1152009"&gt;&lt;b&gt;BBa_K1152009&lt;/b&gt;&lt;/a&gt;'></span>
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                </div>
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                <div class="requirement">
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                    <span class="check"></span>
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                    <span class="requirement">We helped other iGEM teams!</span>
 +
                    <span class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;" data-title="Collaboration" data-placement="left" data-content="In the past months, we &lt;a href='https://2013.igem.org/Team:Heidelberg/Team/Collaboration'&gt;&lt;b&gt;collaborated&lt;/b&gt;&lt;/a&gt; with other student iGEM teams: We sent Freiburg a eukaryotic cell line. Norwich received soil samples from the beautiful forests of Heidelberg and we helped Purdue by participating in their survey. Additionally, we fixed a bug in Cambridge's Gibthon software tool. The parts registry is now properly connected to Gibthon and importing parts directly from the registry is possible (if they accept our pull request on GitHub)."></span>
 +
                </div>
 +
                <div class="requirement">
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                    <span class="check"></span>
 +
                    <span class="requirement">Novel approach to ownership and sharing as well as safety is described!</span>
 +
                    <span  class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;" data-title="NRPS-Designer" data-placement="left"  data-content="The &lt;a href='http://igem2013.bioquant.uni-heidelberg.de/NRPSDesigner/'&gt;&lt;b&gt;NRPSDesigner&lt;/b&gt;&lt;/a&gt; software is our way of sharing our knowledge about NRPS engineering with the iGEM community. During the development and programming of the NRPSDesigner we employed different &lt;a href='https://2013.igem.org/Team:Heidelberg/OpenSource'&gt;&lt;b&gt;open source&lt;/b&gt;&lt;/a&gt; software packages and also improved some of those in order to support the open source programming community. Please feel free to visit our &lt;a href='https://2013.igem.org/Team:Heidelberg/Safety'&gt;&lt;b&gt;Safety page&lt;/b&gt;&lt;/a&gt; also."></span>
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                  <div id="attribution" class="medal"><h8><b>Attribution and Contribution!</b></h8>
 
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                <p>  Thank you for the great help! <span class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px; margin-right:60%;" data-trigger='click',data-placement="left", data-title="...", data-content='Link to sponsors and other donors of stuff and time... '></p></span>
 
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Latest revision as of 03:52, 29 October 2013

Achievements. Introducing NRPS to Synthetic Biology.


Automated Design of Custom Non-Ribosomal Peptide Synthetases


Production of Synthetic Peptides in different engineered E. coli Hosts


Invention of a Universal Tag for Non-Ribosomal Peptide labeling in vivo
Using the Tag for peptide characterization and quantification of production


Application of delftibactin NRP for sustainable Gold Recycling


Introducing our standardized Framework for Production of Synthetic Peptides to the Synbio Community: RFC 99 and RFC 100
Having lots of fun and very much looking forward to the Jamboree in Boston

Medal Requirements. Aiming for Gold.



Best New Standard
We submitted RFC99 and RFC100!
Parts!
Have a look on our different parts!
Attribution and Contribution!
Thank you for the great help!
Bronze Medal Requirements
Team is registered!
Judging form is completed and submitted!
Project description of the Philosopher's Stone online!
Poster is prepared for the European Jamboree in Lyon!
New standard BioBrick is documented!
Silver Medal Requirements
New BioBricks are characterized!
New BioBricks are submitted!
Implications for ethics are pointed out!
Gold Medal Requirements
Functions of existing BioBrick was improved!
We helped other iGEM teams!
Novel approach to ownership and sharing as well as safety is described!
Thanks to

Retrieved from "http://2013.igem.org/Team:Heidelberg/Project/Achievements"