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- | | + | <div id="class"> |
| + | <table width="1024" border="0" class="bg"> |
| + | <tr> |
| + | <td><div id="c1"><ul><li><a href="https://2013.igem.org/Team:BIT/project_AC">>>MORE</a></li></ul></div></td> |
| + | <td><div id="c2"><ul><li><a href="https://2013.igem.org/Team:BIT/project_biosensors">>>MORE</a></li></ul></div></td> |
| + | <td><div id="c3"><ul><li><a href="https://2013.igem.org/Team:BIT/project_microchip">>>MORE</a></li></ul></div></td> |
| + | <td><div id="c4"><ul><li><a href="https://2013.igem.org/Team:BIT/project_hardware">>>MORE</a></li></ul></div></td> |
| + | </tr> |
| + | </table> |
| + | </div> |
| <div id="main"> | | <div id="main"> |
| <div id="left"> | | <div id="left"> |
| <ul> | | <ul> |
| <li><a href="https://2013.igem.org/Team:BIT">HOME</a></li> | | <li><a href="https://2013.igem.org/Team:BIT">HOME</a></li> |
- | <li><a href="https://2013.igem.org/Team:BIT/project_biosensors">BIOSENSORS</a></li> | + | <li><a href="https://2013.igem.org/Team:BIT/Team">TEAM</a></li> |
- | <li><a href="https://2013.igem.org/Team:BIT/project_AC">AMPLIFIER</a></li> | + | <li><a href="https://2013.igem.org/Team:BIT/Project">PROJECT</a></li> |
- | <li><a href="https://2013.igem.org/Team:BIT/project_microchip">MICRO CHIP</a></li> | + | <li><a href="https://2013.igem.org/Team:BIT/Parts">PARTS</a></li> |
- | <li><a href="https://2013.igem.org/Team:BIT/project_hardware">MEASUREMENT</a></li> | + | <li><a href="https://2013.igem.org/Team:BIT/Modeling">MODELING</a></li> |
| + | <li><a href="https://2013.igem.org/Team:BIT/HP">HUMAN PRACTICE</a></li> |
| + | <li><a href="https://2013.igem.org/Team:BIT/Safety">SAFETY</a></li> |
| + | <li><a href="https://2013.igem.org/Team:BIT/Notes">NOTES</a></li> |
| </ul> | | </ul> |
- | </div>
| + | </div> |
| <div id="right"> | | <div id="right"> |
- | <table width="821" border="0" class="bg3"> | + | <table width="824" border="0" class="bg3"> |
| <tr> | | <tr> |
- | <td width="814" class="t1"><p class="aaa"><span class="aaa"><span class="aaa">BIT's </span></span><span class="high">measurement</span></p> | + | <td class="t1">Project</td> |
- | <p class="high"><span class="aaa"><span class="aaa"><span class="aaa">Based on</span> </span></span><a href="#sbb" class="high">Standard Biomedical Bricks</a></p>
| + | |
- | <p class="high"> </p></td>
| + | |
| </tr> | | </tr> |
- | <tr>
| + | |
- | <td class="t2"><p><span class="high">Measurement</span>:</p> | + | <tr> |
- | <p> Ok , Now we have contributed a new sensor , put forward a concept of <a href="https://2013.igem.org/Team:BIT/project_AC">controlled amplifier</a> and are working on optimizing it .But we think this is just a start ,for we can then use this kind of idea to detect nearly all kinds of antibiotics in the future and we are still trying our best to do so . </p>
| + | <td class="t2"> |
- | <p> But a matter is that we can not see the florescence in normal condition ,just like the picture below ,we need UV exiting light , narrowband filter and light sensor to tell us the specific intensity of the light ,we also need to calculate the material we want to detect using our mathematical model . that's so complicated .</p></td>
| + | <a href="https://2013.igem.org/Team:BIT/project_biosensors"><strong>Sensors</strong></a><br> |
- | </tr>
| + | β-lactam Detection Device<br> |
- | <tr>
| + | Tetracycline Detection Device<br> |
- | <td class="t3"><p><img src="https://static.igem.org/mediawiki/2013/d/d1/BITsam.jpg" alt="" width="350"></p>
| + | <a href="https://2013.igem.org/Team:BIT/project_AC"><strong>Amplifier</strong></a><br> |
- | <p class="t2"> here , a small, cheap and handheld device , together with our <a href="https://2013.igem.org/Team:BIT/project_microchip">micro chip</a> , is produced which together with our biological core ,forms a complete detecting system. </p>
| + | <a href="https://2013.igem.org/Team:BIT/project_microchip"><strong>Micro Chip</strong></a><br> |
- | <table width="827" border="0" cellspacing="0" cellpadding="0">
| + | <a href="https://2013.igem.org/Team:BIT/project_hardware"><strong>Hardware</strong></a><br> |
- | <tr>
| + | |
- | <td width="827"><img src="https://static.igem.org/mediawiki/2013/d/d1/BITsam.jpg" alt="" width="278" height="200"><img src="https://static.igem.org/mediawiki/2013/8/85/BITchi.jpg" alt="" height="200"><img src="https://static.igem.org/mediawiki/2013/c/c7/BITdet.jpg" alt="" width="288" height="200"></td>
| + | |
- | </tr>
| + | </td> |
- | <tr>
| + | |
- | <td><p class="t2"><img src="https://static.igem.org/mediawiki/2013/c/cd/BITsys.jpg" alt="" width="819"></p></td>
| + | |
- | </tr>
| + | |
- | </table>
| + | |
- | <p class="t2"><span class="aaa"><span class="high"><span class="t2">Parameters of the system:</span></span></span></p>
| + | |
- | <p class="t2"> Cost: 260RMB/$40 (device & chip) . </p>
| + | |
- | <p class="t2"> Size: 10cmX6.5cmX5cm</p>
| + | |
- | <p class="t2"> Power: 20W Max , 3W Average</p>
| + | |
- | <p class="t2"> Functions: User-define mathematical model . Fast detection . Temperature Control . </p>
| + | |
- | <p class="t2"> Resolution: 5 ng/ml Standard fluorescein sodium , 2~5ng/ml Tet .</p>
| + | |
- | <p class="t2"> The small device uses normal color sensors and light path similar to UV spectrophotometer , but contains a new ,or rather strange mathematical model . a combination of our biological model and relative non-biological equations . </p>
| + | |
- | <p class="t2"><img src="https://static.igem.org/mediawiki/2013/7/77/BITthe.jpg" width="701" height="365"></p>
| + | |
- | <p class="t2"> For the specific Data of the measure system , please click <a href="https://2013.igem.org/Team:BIT/project_data">Here.</a> </p>
| + | |
- | <p class="t2"> </p>
| + | |
- | <p class="t2"><span class="high">Standard Biomedical Bricks (if you have interest)</span><a name="sbb"></a></p>
| + | |
- | <p class="t2"> Well , as for biological detection of harmful materials , such as <span class="aaas"><span class="ww">antibiotics , heavy metals , Aromatic hydrocarbons ,radioactive substances , Pesticide residues</span></span> and so on , we need a biological output in <span class="ww">color , fluroscence , Conductivity , OD value </span>and many other forms .</p>
| + | |
- | <p class="t2"><img src="https://static.igem.org/mediawiki/2013/4/43/BITaa.gif" width="700" height="500"></p>
| + | |
- | <p class="t2"> But those outputs may be so weak , just like our fluorescence , without the <a href="https://2013.igem.org/Team:BIT/project_AC" class="ww">controlled amplifier</a> , it can hardly be seen by our eyes ,even under UV light .</p>
| + | |
- | <p class="t2"> Biomedical machines are used in this case , but those machines can hardly be found out of the lab .</p>
| + | |
- | <p class="t2"> So we put forward <span class="high"><span class="ww">standard biomedical & biological system </span></span>,that is : To design a biological core , finishing the corresponding mathematical model , and a standard biomedical external device . </p>
| + | |
- | <p class="t2"> Just like us , our aim is <span class="ww"><span class="aaa"><span class="ww">Practical Application</span></span></span> . We created a biosensor , an amplifier and their mathematical models . </p>
| + | |
- | <p class="t2"> <span class="ww">Standard biomedical bricks</span> means the specific mathematical models which suits for our low cost sensors .iGEM is an application-oriented contest , so detection needs to be economic and convenient . Now we have many standard electronic sensors , BIT iGEM team has also optimized a processor which has an interface suiting for any kinds of sensors .<span class="ww">what we need to do</span> is to <span class="ww"><span class="t2"><span class="aaa"><span class="ww">build up our engineered bacteria</span></span></span></span>,<span class="ww"> burn the standard mathematical models in the processor</span> and <span class="ww">connect the suitable sensor to the processor</span> . then a complete and application-oriented system is built.just like our detecting system ,we have made many editions :</p>
| + | |
- | <p class="t2"><img src="https://static.igem.org/mediawiki/2013/f/f6/BITqjf.jpg" width="700" height="470"></p>
| + | |
- | <p class="t2"> Then we arrange user-friendly I/O interface to the standard processor ,making a colorful cover to the whole system . that means ,you can achieve any kinds of detection using the same device ,that sounds cool ,isn't it ? .</p>
| + | |
- | <p class="t2"><img src="https://static.igem.org/mediawiki/2013/0/06/BITaaa.jpg" width="700" height="442"></p>
| + | |
- | <p class="t2"> So what we have done at this time is just to simplify the old measurement and provide a new , convenient ,economic measurement which detection can be achieved in kichen . maybe ,some years later ,you can see a "bio-antibiotic detector" in supermarket ,and let's wait for the coming of that day !</p>
| + | |
- | <p class="t2"> We have put forward a concept , and now we have make part of the concept into reality . we will go further on our way to overcome any difficulties ,and we eagerly need partners to fight with us . If you have interest in it </p>
| + | |
- | <p class="t2"> </p>
| + | |
- | <p class="t2"> </p>
| + | |
- | <p class="t2"> </p>
| + | |
- | <p class="t2"> </p>
| + | |
- | <p class="t2"> </p>
| + | |
- | <p class="t2"> </p></td><td width="10"></td>
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| </tr> | | </tr> |
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| </div> | | </div> |
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- | <td> E-mail: yifei0114@bit.edu.cn</td> | + | <td> E-mail:<a href="mailto:yifei0114@bit.edu.cn"> yifei0114@bit.edu.cn</a></td> |
| <td> </td> | | <td> </td> |
| </tr> | | </tr> |
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