Team:Hong Kong CUHK

From 2013.igem.org

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   <h1>Abstract</h1>
   <h1>Abstract</h1>
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   <p2>Polycyclic  aromatic hydrocarbons (PAHs) are harmful to both environment and human health.  We proposed the PAHs degradation system, which contains codon-optimized laccase  from Bacillus sp. HR03 and catechol 1,2-dioxygenase from Pseudomonas putida  KT2440 for Escherichia coli. The...</p2>
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   <p2>To rapidly regulate biological process, we designed a novel transmembrane protein called Voltage Switch (VS), which is a fusion protein utilizing the voltage sensing domain from potassium ion channels. Triggered by a change of potential across the inner membrane, VS can bring targeting enzymes into proximity, thus allowing an instant control of enzymatic reaction...</p2>
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<a href="https://2013.igem.org/Team:Hong_Kong_CUHK/backgroundVS">
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   <h1>Voltage Switch</h1>
   <h1>Voltage Switch</h1>
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   <p2>The voltage-dependent ion channels family are a group of ion channel proteins found to have permeability to ions dependent on  the voltage in the external environment. This family of ion channels are widely  found in neuronal cells...</p2>
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   <p2>Voltage Switch is a response system triggered by a change of potential across the bacterial inner membrane. Components of this system include the transmembrane voltage sensor peptide originated from potassium ion channels, polyproline linker in the inner membrane, glycine serine linker, PDZ domain and PDZ ligand in the periplasm, and glycine serine linker and effectors in the cytosol...</p2>
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Latest revision as of 02:10, 29 October 2013

iGEM CUHK

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