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Team:Wageningen UR/Engineering morphology
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Revision as of 18:17, 8 September 2013
- Safety introduction
- General safety
- Fungi-related safety
- Biosafety Regulation
- Safety Improvement Suggestions
- Safety of the Application
Engineering morphology
Host engineering
Generating single cell factories
Introduction
Synthetic biology doesn’t stop at the level of molecular systems. To expand the scope of this project we have chosen for a multi-level approach, in which we are working on biobricks, proteins, a pathway and also our host. In order to achieve the latter two strategies have been conceived of. In the first we have chosen to harness the power of directed evolution, a powerful tool that not often used in this competition. An explanation for this might lie in the fact that this approach is only semi-rational at best, however we like to argue that this does not make it any less of a powerful mechanism, and neither within the field of synthetic biology. Nonetheless, in order to explore new territories we have chosen for a second, fully rational approach in which we analyze the transcriptome of two distinct phenotypes; the mycelial and the single cell.
Abstract
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