Team:IIT Delhi/Safety

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  style="vertical-align: top; text-align: center; width: 684px; background-color: rgb(51, 51, 51);"><big><big><big
  style="vertical-align: top; text-align: center; width: 684px; background-color: rgb(51, 51, 51);"><big><big><big
  style="font-family: Palatino Linotype;"><span
  style="font-family: Palatino Linotype;"><span
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  style="color: white;">Abstract</span><br
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       <small><small><span style="color: white;">pH
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            <td style="vertical-align: top; text-align: center;"><big><big><big
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      <big><big><big
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      <font size="+2"><span style="color: white;">pH
induced response
induced response
elicited by certain promoters in bacteria may have major practical
elicited by certain promoters in bacteria may have major practical
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mathematical model has been developed to simulate the experimental
mathematical model has been developed to simulate the experimental
findings. The present study will form the basis for further research in
findings. The present study will form the basis for further research in
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the field of synthetic biology.</span></small></small></big></big></big></td>
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the field of synthetic biology.</span></font></big></big></big></td>
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Revision as of 12:13, 20 September 2013

Navigation-Top




iGEM IIT Delhi

Project pH. Coli





Abstract

pH induced response elicited by certain promoters in bacteria may have major practical applications. The response can be targeted for specific pH ranges, for example in tracking the anomalies associated with the gut micro-biota or detecting pH inside a bioreactor. There are only limited studies reported in the area. In the present project, a genetic circuit has been created, using the promoters of the acid shock response gene from E.coli and the F0F1 ATPase operon from C. glutamicum that produces a pH dependent colour gradient, much like a universal pH indicator. A mathematical model has been developed to simulate the experimental findings. The present study will form the basis for further research in the field of synthetic biology.


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