Team:Kyoto

From 2013.igem.org

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RNA Module
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A final objective of natural science is understanding natural phenomena generally with simple ideas such as formulas.
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For example, Physists explains motion of elementary particles or the orbits of heavenly bodies with simple formulas.
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RNA has some different characters from proteins; faster degradation, easier structure prediction, easier synthes and so on.
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On the other hand, few biologists have explained vital phenomena with formulas. Why vital phenomena is hard to be explained with formula?  The reason may be that biologists tend to pause or hold back in thinking about how to apply formulas to vital phenomena.
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Therefore, we focused on RNA. We constucted gene transcriptional activator, repressor, and expression reporter from RNA.
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We want to promote biology's developping through stopping a gap between dry work and wet work. Therefore we recognized usability of dry work and gap between dry and wet and examined how stop the gap by considering Turing Pattern and oscillator composed of protein and RNA for example.
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This means it is possible to construct a new type of gene circuit by RNA. (This RNA system gives a new possibility to synthetic biology)
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Turing Model
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On earth, there are various animals which have unique patterns on their skin A.Turing, a mathematician, explained this well-balanced pattern creating system by using only two simple formulae, Reaction-Diffusion Model.  
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Using E.coli, we examined whether it is able to create a pattern on the plate by this system.
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Revision as of 16:29, 27 September 2013

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A final objective of natural science is understanding natural phenomena generally with simple ideas such as formulas. For example, Physists explains motion of elementary particles or the orbits of heavenly bodies with simple formulas. On the other hand, few biologists have explained vital phenomena with formulas. Why vital phenomena is hard to be explained with formula? The reason may be that biologists tend to pause or hold back in thinking about how to apply formulas to vital phenomena. We want to promote biology's developping through stopping a gap between dry work and wet work. Therefore we recognized usability of dry work and gap between dry and wet and examined how stop the gap by considering Turing Pattern and oscillator composed of protein and RNA for example.

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