Team:Evry/Modeling

From 2013.igem.org

(Difference between revisions)
(→Modeling:)
Line 1: Line 1:
-
{| style="color:#1b2c8a;background-color:#0c6;" cellpadding="3" cellspacing="1" border="1" bordercolor="#fff" width="62%" align="center"
+
{{:Team:Evry/template_v1}}
-
!align="center"|[[Team:Evry|Home]]
+
<html>
-
!align="center"|[[Team:Evry/Team|Team]]
+
-
!align="center"|[https://igem.org/Team.cgi?year=2013&team_name=Evry Official Team Profile]
+
-
!align="center"|[[Team:Evry/Project|Project]]
+
-
!align="center"|[[Team:Evry/Parts|Parts Submitted to the Registry]]
+
-
!align="center"|[[Team:Evry/Modeling|Modeling]]
+
-
!align="center"|[[Team:Evry/Notebook|Notebook]]
+
-
!align="center"|[[Team:Evry/Safety|Safety]]
+
-
!align="center"|[[Team:Evry/Attributions|Attributions]]
+
-
|}
+
-
= Modeling: =
+
<h1>Modeling:</h1>
The modeling part is planned around 4 main targets:
The modeling part is planned around 4 main targets:
<ul>
<ul>
-
     <li>[[Growth of an iron-chelating bacterial population]]</li>
+
     <li>Growth of an iron-chelating bacterial population
-
     <li>[[Risk assessment : forecast, control, auto-regulation, ...]]</li>
+
     <li>Risk assessment : forecast, control, auto-regulation, ...
-
     <li>[[Bacterial activity : iron-chelation rate, avidity (cellular scale)]]</li>
+
     <li>Bacterial activity : iron-chelation rate, avidity (cellular scale)
-
     <li>[[Intestine mapping and interactions]]</li>
+
     <li>Intestine mapping and interactions
</ul>
</ul>
-
== First approach: ==
+
<h1>First approach: </h1>
For a better understanding of the bacteria our team is going to produce, we chose to first focus on the growth of an iron-chelating bacterial population.  
For a better understanding of the bacteria our team is going to produce, we chose to first focus on the growth of an iron-chelating bacterial population.  
-
Let us suppose we have <math>N_0</math> initial siderophore-producing bacterias in a closed system with dissolved iron. Monitoring the evolution of those bacterias, the dissolved iron, the siderophores and the chelated iron through a simple model will help our biologists tune their constructions.<br/><br/>
+
<br/>Let us suppose we have <math>N_0</math> initial siderophore-producing bacterias in a closed system with dissolved iron. Monitoring the evolution of those bacterias, the dissolved iron, the siderophores and the chelated iron through a simple model will help our biologists tune their constructions.<br/><br/>
<img:systeme differentiel/><br/><br/>
<img:systeme differentiel/><br/><br/>
where <math>\alpha</math> is the Mc Kellar adaptation factor:<br/><br/>
where <math>\alpha</math> is the Mc Kellar adaptation factor:<br/><br/>
<img:McKellar><br/><br/>
<img:McKellar><br/><br/>

Revision as of 11:54, 16 July 2013

Modeling:

The modeling part is planned around 4 main targets:
  • Growth of an iron-chelating bacterial population
  • Risk assessment : forecast, control, auto-regulation, ...
  • Bacterial activity : iron-chelation rate, avidity (cellular scale)
  • Intestine mapping and interactions

First approach:

For a better understanding of the bacteria our team is going to produce, we chose to first focus on the growth of an iron-chelating bacterial population.
Let us suppose we have N_0 initial siderophore-producing bacterias in a closed system with dissolved iron. Monitoring the evolution of those bacterias, the dissolved iron, the siderophores and the chelated iron through a simple model will help our biologists tune their constructions.



where \alpha is the Mc Kellar adaptation factor:



Retrieved from "http://2013.igem.org/Team:Evry/Modeling"