PennApps
Our final product was a gel analysis app which automates the process of interpreting DNA bands run through gel electrophoresis. This app, entitled MaGellin, complements our digestion assay and reports the extent of on-target and off-target methylation, greatly simplifying data analysis for the experimenter. Unlike other gel analysis programs, MaGellin interprets plasmid sequences, understands methylation patterns, and assesses targeted methylation based on a gel image.
Learn more about MaGellin on our software page.
MaGellin is a robust platform that can easily be adjusted for other gel analysis problems, such as interpreting COBRA and quantifying PCR yields. Our code is open-source, and we encourage researchers to adapt it to various needs. We would like to collaborate with other iGEM teams to expand the range of gel analysis tasks MaGellin performs.