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==== peripheral tolerance ==== | ==== peripheral tolerance ==== | ||
| - | + | self-reactive B cells that escape this test and go on to mature may still be removed from the repertoire | |
| - | escape this test and go on to mature may still be removed from the repertoire | + | |
after they have left the bone marrow, a process that produces peripheral | after they have left the bone marrow, a process that produces peripheral | ||
tolerance. | tolerance. | ||
Revision as of 03:49, 19 April 2014
Contents |
Section VI. Take Home Essay
What is immunological tolerance?
immunological tolerance also called immune toleranceTemplate loop detected: Template:LangWithName,it is mean the immune system do not response to the specific antigen. It can divided into self toleranceTemplate loop detected: Template:LangWithName & induced toleranceTemplate loop detected: Template:LangWithName.
self tolerance
生物體對自身體細胞的抗原不會產生反應
induced tolerance
對外來抗原不會產生免疫反應，是通過誘導的方式產生。induced tolerance又可分為central toleranceTemplate loop detected: Template:LangWithName、peripheral toleranceTemplate loop detected: Template:LangWithName與acquired toleranceTemplate loop detected: Template:LangWithName。
central tolerance
The tolerance produced at this stage of B-cell development is known as central tolerance because it arises in a central lymphoid organ, the bone marrow.
peripheral tolerance
self-reactive B cells that escape this test and go on to mature may still be removed from the repertoire after they have left the bone marrow, a process that produces peripheral tolerance.
acquired tolerance
How do our Immune system recognize and destroy Cancer cells
reference:
- Janeway's Immunobiology 8th
- Wiki
