Team:Peking/Project

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You are provided with this team page template with which to start the iGEM season.  You may choose to personalize it to fit your team but keep the same "look." Or you may choose to take your team wiki to a different level and design your own wiki.  You can find some examples <a href="https://2008.igem.org/Help:Template/Examples">HERE</a>.
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!align="center"|[[Team:Peking|Home]]
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!align="center"|[[Team:Peking/Team|Team]]
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!align="center"|[https://igem.org/Team.cgi?year=2013&team_name=Peking Official Team Profile]
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!align="center"|[[Team:Peking/Project|Project]]
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!align="center"|[[Team:Peking/Parts|Parts Submitted to the Registry]]
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!align="center"|[[Team:Peking/Modeling|Modeling]]
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!align="center"|[[Team:Peking/Notebook|Notebook]]
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!align="center"|[[Team:Peking/Safety|Safety]]
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!align="center"|[[Team:Peking/Attributions|Attributions]]
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== '''Overall project''' ==
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Tell us more about your project. Give us background. Use this is the abstract of your project. Be descriptive but concise (1-2 paragraphs)
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== Project Details==
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=== Part 2 ===
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=== The Experiments ===
 
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<a href="https://2013.igem.org/Team:Peking">home</a>
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<li><a>Existing Biosensors</a></li>
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<li><a>Plug-ins & Expansion</a></li>
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                                <li><a>Application</a></li>
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<div id="ProjectTitle">
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<h1 id="ProjectName">AROMATICS BUSTED</h1>
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                <h1 id="ProjectSubname">A FAST, EASY AND ACCURATE METHOD TO DETECT TOXIC AROMATIC COMPOUNDS</h1>
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            <p id="AbstractContent">As aromatic pollution levels rise, and along with it the environmental and health hazards that it presents, finding a better way of detecting these aromatic compounds becomes more and more important. Some prokaryotes, including <I>Escherichia coli</I> and <I>Pseudomonas putida</I>, naturally produce proteins capable of both detecting toxic aromatic molecules and regulating the transcription of corresponding catabolic genes. However, these naturally existing biosensors are limited by their detection range, expression leakage, and induction ratio.<br/><br/>Using these proteins, our team designed a series of improved aromatic sensors and combined them with related enzymes from their original catabolic pathways to increase the molecule detection range of these sensors. In order to semi-quantitatively measure the concentrations of target compounds, we constructed a biological band-pass circuit, enabling our sensors to detect the concentrations of target compounds within a certain range. In sum, we have been working on a fast, easy and accurate way to detect toxic aromatic compounds.</p>
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        </div>       
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<img id="AcknowledgementBox" src="https://static.igem.org/mediawiki/igem.org/c/c4/Peking_Sponsors.jpg">
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<!--end of acknowledgement box-->
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=== Part 3 ===
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== Results ==
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Revision as of 10:46, 7 September 2013

AROMATICS BUSTED

A FAST, EASY AND ACCURATE METHOD TO DETECT TOXIC AROMATIC COMPOUNDS

As aromatic pollution levels rise, and along with it the environmental and health hazards that it presents, finding a better way of detecting these aromatic compounds becomes more and more important. Some prokaryotes, including Escherichia coli and Pseudomonas putida, naturally produce proteins capable of both detecting toxic aromatic molecules and regulating the transcription of corresponding catabolic genes. However, these naturally existing biosensors are limited by their detection range, expression leakage, and induction ratio.

Using these proteins, our team designed a series of improved aromatic sensors and combined them with related enzymes from their original catabolic pathways to increase the molecule detection range of these sensors. In order to semi-quantitatively measure the concentrations of target compounds, we constructed a biological band-pass circuit, enabling our sensors to detect the concentrations of target compounds within a certain range. In sum, we have been working on a fast, easy and accurate way to detect toxic aromatic compounds.

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