Team:SCAU-China

What are we doing?

    Synthetic organophosphorus (OP) compounds have been used as pesticides, petroleum additive and warfare agents, which is a highly toxic contaminant to agro-environment and food security. Parathion is a typical representative of organophosphorus pesticides. This year, our goal is to construct a p-Nitrophenol sensor in E coli., which is the degradation product of parathion, in order to reflect the existence of parathion. Considering the biosafety problem after its release, we designed a suicide system in which the lethal genes are only triggered by declining p-Nitrophenol concentration. This will enable the bacteria to commit suicide when p-Nitrophnol is sufficiently degraded.