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Team:TecMonterrey
From 2013.igem.org
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By exploiting the inherent ability of facultative anaerobic bacteria to colonize and grow in tumoral environments, this project aims to combine 3 different approaches in one bacterial system: the development of a genetically engineered Escherichia coli capable of producing two cancer specific apoptosis inducing proteins, a secretion system for the delivery of therapeutic proteins, and the design of a control mechanism confining the production of the therapeutic proteins only in tumor-specific regions. | By exploiting the inherent ability of facultative anaerobic bacteria to colonize and grow in tumoral environments, this project aims to combine 3 different approaches in one bacterial system: the development of a genetically engineered Escherichia coli capable of producing two cancer specific apoptosis inducing proteins, a secretion system for the delivery of therapeutic proteins, and the design of a control mechanism confining the production of the therapeutic proteins only in tumor-specific regions. | ||
Revision as of 23:09, 9 August 2013
Project descriptionBy exploiting the inherent ability of facultative anaerobic bacteria to colonize and grow in tumoral environments, this project aims to combine 3 different approaches in one bacterial system: the development of a genetically engineered Escherichia coli capable of producing two cancer specific apoptosis inducing proteins, a secretion system for the delivery of therapeutic proteins, and the design of a control mechanism confining the production of the therapeutic proteins only in tumor-specific regions. |  |
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