Team:Alberta

From 2013.igem.org

(Difference between revisions)
Line 1: Line 1:
-
<!--<html>
+
<html>
<div id="box" style="width: 700px; margin-left: 137px; padding: 5px; border: 3px solid #000; background-color: #000000;">
<div id="box" style="width: 700px; margin-left: 137px; padding: 5px; border: 3px solid #000; background-color: #000000;">
<div id="template" style="text-align: center; font-weight: bold; font-size: large; color: #f6f6f6; padding: 5px;">
<div id="template" style="text-align: center; font-weight: bold; font-size: large; color: #f6f6f6; padding: 5px;">
Line 48: Line 48:
<html><a class="twitter-timeline" href="https://twitter.com/iGEMAlberta" data-widget-id="368908364702437377">Tweets by @iGEMAlberta</a>
<html><a class="twitter-timeline" href="https://twitter.com/iGEMAlberta" data-widget-id="368908364702437377">Tweets by @iGEMAlberta</a>
<script>!function(d,s,id){var js,fjs=d.getElementsByTagName(s)[0],p=/^http:/.test(d.location)?'http':'https';if(!d.getElementById(id)){js=d.createElement(s);js.id=id;js.src=p+"://platform.twitter.com/widgets.js";fjs.parentNode.insertBefore(js,fjs);}}(document,"script","twitter-wjs");</script></html>
<script>!function(d,s,id){var js,fjs=d.getElementsByTagName(s)[0],p=/^http:/.test(d.location)?'http':'https';if(!d.getElementById(id)){js=d.createElement(s);js.id=id;js.src=p+"://platform.twitter.com/widgets.js";fjs.parentNode.insertBefore(js,fjs);}}(document,"script","twitter-wjs");</script></html>
-
 
-
---------- -->
 
-
<cfheader name="X-XSS-Protection" value="0">
 
-
<html>
 
-
  <head>
 
-
    <link href="http://netdna.bootstrapcdn.com/twitter-bootstrap/2.3.2/css/bootstrap-combined.min.css" rel="stylesheet">
 
-
  <style type="text/css">
 
-
    .titlebar {
 
-
      height:130px;
 
-
      width:100%;
 
-
    }
 
-
    .bin {
 
-
      background:url('/wiki/images/thumb/2/26/Background.png/541px-Background.png');
 
-
      height:100%;
 
-
    }
 
-
    .nav-icon {
 
-
      background-image:url('https://static.igem.org/mediawiki/2013/6/69/Nav-icon.png');
 
-
      display:inline-block;
 
-
      position:fixed;
 
-
      width:23px;
 
-
      height:37px;
 
-
      margin-top:-17px;
 
-
      margin-left:-20px;
 
-
    }
 
-
    .block {
 
-
      background-color:white;
 
-
      border:1px grey solid;
 
-
      padding:10px;
 
-
      margin:10px;
 
-
      border-radius:5px;
 
-
      box-shadow: 0px 0px 30px #444444;
 
-
    }
 
-
    .titlebar h3, h4 {
 
-
      text-align:center;
 
-
    }
 
-
    .opaque {
 
-
      background-color:white;
 
-
      width:975px;
 
-
      margin: 0 auto;
 
-
    }
 
-
    .sidebar {
 
-
      float:left;
 
-
      padding: 15px 0px 0px 40px;
 
-
    }
 
-
    .main {
 
-
      position:relative;
 
-
      float:right;
 
-
      width:720px;
 
-
    }
 
-
    .clear {
 
-
      clear:both;
 
-
    }
 
-
    .ualberta-logo {
 
-
      padding: 10px;
 
-
      position:fixed;
 
-
      left:50%
 
-
      margin-left:-250px;
 
-
      width:180px;
 
-
    }
 
-
    .igem-logo {
 
-
      position:relative;
 
-
      left:50%;
 
-
      margin-left:250px;
 
-
      margin-top:-100px;
 
-
      width: 150px;
 
-
    }
 
-
    .igem-bar {
 
-
      postion:fixed;
 
-
      height:40px;
 
-
    }
 
-
  </style>
 
-
  </head>
 
-
  <body>
 
-
    <div class="bin">
 
-
      <div class="navbar navbar-fixed-top navbar-absolute opaque">
 
-
        <div class="titlebar">
 
-
          <a href="#"><img src="/wiki/images/b/b3/Ualberta-logo.png" class="ualberta-logo"></img></a>
 
-
          <h3>The Littlest Mapmaker</h1>
 
-
          <h4>"Exploration into the world of <a href="#">DNA Computing</a>"<br/>
 
-
            Team Alberta: University of Alberta</h4>
 
-
          <a href="#"><img src="https://static.igem.org/mediawiki/2013/a/ad/IGem-logo.png" class="igem-logo"></img></a>
 
-
        </div>
 
-
        <div class="navbar-inner" >
 
-
          <a class="btn btn-navbar" data-toggle="collapse" data-target=".nav-collapse">
 
-
            <span class="icon-bar"></span>
 
-
            <span class="icon-bar"></span>
 
-
            <span class="icon-bar"></span>
 
-
          </a>
 
-
          <div class="nav-collapse collapse">
 
-
          <ul class="nav">
 
-
            <li class="active"><a  href="home.html" style="margin-left:5px;"><i class="nav-icon"></i> Home</a></li>
 
-
            <li class="dropdown">
 
-
              <a id="project" role="button" class="dropdown-toggle" data-toggle="dropdown" href="#">Project <b class="caret"></b></a>
 
-
              <ul class="dropdown-menu" role="menu" aria-labelledby="project">
 
-
                <li><a href="#">Overview</a></li>
 
-
                <li><a href="methodology.html">Methodology</a></li>
 
-
                <li><a href="#">Applications</a></li>
 
-
              </ul>
 
-
            </li>
 
-
            <li class="dropdown">
 
-
              <a id="notebook" role="button" class="dropdown-toggle" data-toggle="dropdown" href="#">Notebook <b class="caret"></b></a>
 
-
              <ul class="dropdown-menu" role="menu" aria-labelledby="notebook">
 
-
                <li><a href="#">Timeline</a></li>
 
-
                <li><a href="#">Results</a></li>
 
-
                <li><a href="#">BioBricks</a></li>
 
-
              </ul>
 
-
            </li>
 
-
            <li class="dropdown">
 
-
              <a id="team" role="button" class="dropdown-toggle" data-toggle="dropdown" href="#">Team <b class="caret"></b></a>
 
-
              <ul class="dropdown-menu" role="menu" aria-labelledby="team">
 
-
                <li><a href="#">Roster</a></li>
 
-
                <li><a href="#">Sponsers</a></li>
 
-
              </ul>
 
-
            </li>
 
-
            <li class="dropdown">
 
-
              <a id="humanpractices" role="button" class="dropdown-toggle" data-toggle="dropdown" href="#">Human Practices <b class="caret"></b></a>
 
-
              <ul class="dropdown-menu" role="menu" aria-labelledby="humanpractices">
 
-
                <li><a href="#">Safety</a></li>
 
-
                <li><a href="#">Community</a></li>
 
-
              </ul>
 
-
            </li>
 
-
          </ul>
 
-
          <a href="#" class="pull-right"><img src="https://static.igem.org/mediawiki/2013/a/ad/IGem-logo.png" class="igem-bar"></img></a>
 
-
          </div>
 
-
        </div>
 
-
      </div>
 
-
<div id="box" style="width: 700px; margin-left: 137px; padding: 5px; border: 3px solid #000; background-color: #000000;">
 
-
<div id="template" style="text-align: center; font-weight: bold; font-size: large; color: #f6f6f6; padding: 5px;">
 
-
For visitors: this site is currently under construction. Please contact our Student Liason, Dawson at daocun@ualberta.ca, for more information on our current project and how to support us!
 
-
</div>
 
-
</div>
 
-
      <div class="sidebar">
 
-
          <a href="#">
 
-
          <img id="saying" href="#" data-toggle="popover"
 
-
          data-placement="right"
 
-
          data-content="Welcome to the Team Alberta Wiki"
 
-
          data-trigger="hover focus" data-container="body" src="/wiki/images/7/7d/SideChar.png"
 
-
          ></img>
 
-
          </a>
 
-
      </div>
 
-
      <div class="main">
 
-
      <div class="block">
 
-
        <img src="/wiki/images/e/e8/Mapmaker-banner.jpg"></img>
 
-
      </div>
 
-
      <div class="block">
 
-
      <p>
 
-
        Project abstract here - stating the nature of the project as simply and
 
-
        succinctly as possible. Lorem ipsum dolor sit amet, consectetuer
 
-
        adipiscing elit. Aenean commodo ligula eget dolor. Aenean massa. Cum
 
-
        sociis natoque penatibus et magnis dis parturient montes, nascetur
 
-
        ridiculus mus. Donec quam felis, ultricies nec, pellentesque eu, pretium
 
-
        quis, sem. Nulla consequat massa quis enim. Donec pede justo, fringilla
 
-
        vel, aliquet nec, vulputate eget, arcu. In enim justo, rhoncus ut,
 
-
        imperdiet a, venenatis vitae, justo. Nullam dictum felis eu pede mollis
 
-
        pretium. Integer tincidunt. Cras dapibus. Vivamus elementum semper nisi.
 
-
      </p>
 
-
      </div>
 
-
      <div class="block">
 
-
      <p>
 
-
        Twitter Feed Widget - @iGEMAlberta
 
-
      </p>
 
-
      </div>
 
-
      <div class="block">
 
-
      <p>
 
-
        Project abstract here - stating the nature of the project as simply and
 
-
        succinctly as possible. Lorem ipsum dolor sit amet, consectetuer
 
-
        adipiscing elit. Aenean commodo ligula eget dolor. Aenean massa. Cum
 
-
        sociis natoque penatibus et magnis dis parturient montes, nascetur
 
-
        ridiculus mus. Donec quam felis, ultricies nec, pellentesque eu, pretium
 
-
        quis, sem. Nulla consequat massa quis enim. Donec pede justo, fringilla
 
-
        vel, aliquet nec, vulputate eget, arcu. In enim justo, rhoncus ut,
 
-
        imperdiet a, venenatis vitae, justo. Nullam dictum felis eu pede mollis
 
-
        pretium. Integer tincidunt. Cras dapibus. Vivamus elementum semper nisi.
 
-
      </p>
 
-
      </div>
 
-
      </div>
 
-
      <div class="clear"></div>
 
-
    </div>
 
-
   
 
-
 
-
    <script src="http://code.jquery.com/jquery-2.0.3.min.js"></script>
 
-
    <script src="http://netdna.bootstrapcdn.com/twitter-bootstrap/2.3.2/js/bootstrap.min.js"></script>
 
-
    <script>$(function (){ $("#saying").popover({html:true, delay: {hide:1000}});});</script>
 
-
  </body>
 
-
</html>
 

Revision as of 21:21, 28 August 2013

For visitors: this site is currently under construction. Please contact our Student Liason, Dawson at daocun@ualberta.ca, for more information on our current project and how to support us!


Alberta logo.png


Team Alberta represents the University of Alberta, from Edmonton. Our project, "The Littlest Mapmakers", is an attempt to create a biological computer capable of solving the Traveling Salesman Problem



The traveling salesman problem is a mathematical optimization problem that was first formally described in 1930, and has been intensively studied in the computer sciences as a benchmark for optimization algorithms. The problem asks:

Given a set of cities (or other destinations), and a list of the distances (or the travel time, fuel consumption, et cetera) between each pair of those cities, what is the shortest possible route that travels to every city exactly once, and then returns to the origin city?
In our project, we use DNA to compute solutions by converting all of the elements of the problem into representative sequences of DNA: cities become selectable marker genes (specifically, antibiotic resistance genes), paths between the cities become short, sticky-ended linkers (each of which is only able to ligate to two specific “city” strands), and the distance of a given path is represented by the concentration of the corresponding linker in solution. These pieces of DNA are successively ligated together to produce plasmids that signify “routes”, where the order in which the genes appear in the plasmid indicates the order in which the cities are visited.

Sample product.pngSample route.png

The resulting plasmids are transformed into a bacterial culture, so that we can select for only those plasmids that include every city in the list. Then, plasmid DNA is extracted from the surviving bacterial colonies and analyzed to determine which plasmid (and thus which route) occurred the most frequently. This route, the one most favoured by the ligation reactions, is the optimal route!



Home Team Official Team Profile Project Parts Submitted to the Registry Modeling Notebook Safety Attributions