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Natural products

Secondary metabolites are the products of metabolism not essential for normal growth, development or reproduction of an organism. They meet the secondary requirements of the producing organisms, empower them to survive interspecies competition, provide defensive mechanisms and facilitate reproductive processes. Well known sources of secondary metabolites are plants, bacteria, fungi and marine organisms such as sponges, tunicates, corals and snails.

Extensive applications

Well-known medical uses

Secondary metabolites are well-know as antimicrobials. Currently, many secondary metabolites have proved to be effective as antibacterial or antifungal agents, anticancer drugs, cholesterol-lowering agents, immunosuppressants, antiparasitic agents, herbicides, diagnostics, and tools for research.

Exploiting the therapic potential from fungi

In addition to their known roles in combating disease, secondary metabolites reveal surprising additional activities which may be possible solutions to other treatment-lacked diseases. Many antibiotics, bacterial pigments, plant terpenoids,are also found to have anti-HIV, antitumor, anti-ageing, immunosuppressant, antiprotozoal and antihelminth activities, thus exhibiting multifarious applications in the sphere of medicine.

Unraveling the novel applications of known secondary metabolites and exploiting a myriad of sources as microbes, plants and higher animals for screening new secondary metabolites are paving the way to treat “untreatable diseases”, and help reduce mortality rates. The study of those useful activities of secondary against life-threatening diseases may catalyze further efforts to apply them against other forms of human disease.

Exploiting the therapic potential from fungi

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