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| | <div id="description" class="page" data-stellar-background-ratio="0.5"><div class="boxwrap" data-stellar-ratio="1.25"><div class="box"><div class="title">E.colightuner</div><span | | <div id="description" class="page" data-stellar-background-ratio="0.5"><div class="boxwrap" data-stellar-ratio="1.25"><div class="box"><div class="title">E.colightuner</div><span |
| | | | |
| - | class="team">by NCTU_Formosa</span><div class="wordbox"><p>We have proven a sRNA-regulated system of our own to be an effective and competent way for regulating gene expressions. </p> | + | class="team">by NCTU_Formosa</span><div class="wordbox"><p>Like a tuner, we wanted to construct a E.coli which can make |
| - | <p>Recent studies have shown that sRNA-mediated regulation is an important factor to bacterial growth. sRNAs work by base pairing with limited or extended complementary target mRNAs, regulating protein productions. Using sRNA mechanism, we can control gene expression in RNA level, in contrast to common promoters that functions on DNA level. Since the existing sRNAs in Escherishia Coli have important functions in other metabolic processes, we designed an artificial sRNA with high specificity to avoid undesired base binding in vitro.</p> | + | different products as environment changes. By using factors |
| - | <p>By using the sRNA-regulated system, red light induced ooperator, and thirty seven degree Celsius ribosome binding site (RBS), we constructed a manipulatable system that is capable of expressing four different genes under different conditions. In other words, it is a multitask machine.</p></div></div></div></div> | + | like small RNA, light and temperature, a multiple regulated-system |
| | + | can be achieved.</p> |
| | + | |
| | + | <p>First, we have proven a sRNA of our own to be an effective and |
| | + | competent way for regulating gene expressions.</p> |
| | + | |
| | + | <p>Second, a light-regulated system have been built by a new biobrick |
| | + | called P<sub>red</sub>. In the presence of red light, it can turn on |
| | + | the downstream gene.</p> |
| | + | |
| | + | <p>Third, using the character of RNA thermometer, we constructed a |
| | + | temperature-regulated system. It is an RBS can detect temperature |
| | + | by change its mRNA secondary structure.</p> |
| | + | |
| | + | <p> |
| | + | In conclusion, combining the three regulated-system, |
| | + | a multitask machine-a manipulatable system that is capable of |
| | + | expressing four different genes under different conditions- is |
| | + | available. </p> |
| | + | |
| | + | </div></div></div></div> |
| | <div id="social" class="page" data-stellar-background-ratio="0.5"> | | <div id="social" class="page" data-stellar-background-ratio="0.5"> |
| | <p class="bigtitle">Bringing back <span class="em">wiki</span> <span class="em2">the way what it was meant to be.</span></p> | | <p class="bigtitle">Bringing back <span class="em">wiki</span> <span class="em2">the way what it was meant to be.</span></p> |
Bringing back wiki the way what it was meant to be.
The core value of wiki are the openness and its coeditable property. As people tried to beautify the pages, too often that the wiki becomes merely a work handled by one person. It digresses from the core value of iGEM. Therefore, to bring back its role, we build a system not only more user-friendly and eye-pleasing but also coeditable and smart.
We believe that wiki is a platform for the iGEMers and the future iGEMers. It stands for sharing. It is meant for cooperation. It ought to be a stage that brings people together for knowledge and the value that lies with people.
Utilizing wiki markup language and BioBricks registry
To layout the pages, the wiki site is often completely written by HTML rather than the originally expected wiki markup language. We believe that wiki language encourages users to be more involved into the project since it's easy to use. Thus, we build a website letting users to edit contents by wiki language but at the same time have a cleaner layout by HTML.
Hence, for the Biobricks page, the table is directly fetched from the Biobrick Registry website. Not only it gets timely updates when new parts are registered, but it intertwines wiki and part wiki into a unique iGEM-centric system.
Responsible design that re-layouts for different resolution
Our wiki site implements a more modern method to create the layout. As screen size changes, the text flows and the layout rearranges accordingly. It supports various screen size down from smartphones and up to computers. To be future-proof, it's touch-friendly and can even support large width devices such as 4KTV!
Contents in wiki are easily editable
When iGEMers log in 2013.igem.org, "Edit" link for each sections appears automatically. Users can click into specific section to modify it. The history log of the page (link located at the top of the screen) can show the section modified and the user who modified it. Since editing contents becomes so straight-forward, our team members edit it spontaneously. We believe the coeditability suggests the spirit of cooperating and sharing, which are what wiki ought to be. Please check out the history log of our project page.
User-friendly functions
To elevate the user experience, we introduce a submenu that fix on the screen when scroll though the page. It serve as a normal menu that links to each sections. So what's special about it? It is so smart that it shows the place we're currently browsing, and links to sub-section that collapsed at first will expand automatically.
We also introduce buttons for changing the font size and a button that can back to the top of the page when page is scrolled down. This wiki is also friendly for blind and visually impaired people that use screen reading softwares.
Auto-generated menu that powered by wiki system
The core value of wiki are the openness and its coeditable property. As people tried to beautify the pages, too often that the wiki becomes merely a work handled by one person. It digresses from the core value of iGEM. Therefore, to bring back its role, we build a system not only more user-friendly and eye-pleasing but also coeditable and smart.
Following the requirements for iGEM wiki site
https://2013.igem.org/Requirements/Wiki
The core value of wiki are the openness and its coeditable property. As people tried to beautify the pages, too often that the wiki becomes merely a work handled by one person. It digresses from the core value of iGEM. Therefore, to bring back its role, we build a system not only more user-friendly and eye-pleasing but also coeditable and smart.
"
Bringing back wiki the way what it was meant to be.
The core value of wiki are the openness and its coeditable property. As people tried to beautify the pages, too often that the wiki becomes merely a work handled by one person. It digresses from the core value of iGEM. Therefore, to bring back its role, we build a system not only more user-friendly and eye-pleasing but also coeditable and smart.
We believe that wiki is a platform for the iGEMers and the future iGEMers. It stands for sharing. It is meant for cooperation. It ought to be a stage that brings people together for knowledge and the value that lies with people.
Utilizing wiki markup language and BioBricks registry
To layout the pages, the wiki site is often completely written by HTML rather than the originally expected wiki markup language. We believe that wiki language encourages users to be more involved into the project since it's easy to use. Thus, we build a website letting users to edit contents by wiki language but at the same time have a cleaner layout by HTML.
Hence, for the Biobricks page, the table is directly fetched from the Biobrick Registry website. Not only it gets timely updates when new parts are registered, but it intertwines wiki and part wiki into a unique iGEM-centric system.
Responsible design that re-layouts for different resolution
Our wiki site implements a more modern method to create the layout. As screen size changes, the text flows and the layout rearranges accordingly. It supports various screen size down from smartphones and up to computers. To be future-proof, it's touch-friendly and can even support large width devices such as 4KTV!
Contents in wiki are easily editable
When iGEMers log in 2013.igem.org, "Edit" link for each sections appears automatically. Users can click into specific section to modify it. The history log of the page (link located at the top of the screen) can show the section modified and the user who modified it. Since editing contents becomes so straight-forward, our team members edit it spontaneously. We believe the coeditability suggests the spirit of cooperating and sharing, which are what wiki ought to be. Please check out the history log of our project page.
User-friendly functions
To elevate the user experience, we introduce a submenu that fix on the screen when scroll though the page. It serve as a normal menu that links to each sections. So what's special about it? It is so smart that it shows the place we're currently browsing, and links to sub-section that collapsed at first will expand automatically.
We also introduce buttons for changing the font size and a button that can back to the top of the page when page is scrolled down. This wiki is also friendly for blind and visually impaired people that use screen reading softwares.
Auto-generated menu that powered by wiki system
The core value of wiki are the openness and its coeditable property. As people tried to beautify the pages, too often that the wiki becomes merely a work handled by one person. It digresses from the core value of iGEM. Therefore, to bring back its role, we build a system not only more user-friendly and eye-pleasing but also coeditable and smart.
Following the requirements for iGEM wiki site
https://2013.igem.org/Requirements/Wiki
The core value of wiki are the openness and its coeditable property. As people tried to beautify the pages, too often that the wiki becomes merely a work handled by one person. It digresses from the core value of iGEM. Therefore, to bring back its role, we build a system not only more user-friendly and eye-pleasing but also coeditable and smart.