Team:Freiburg/main2
From 2013.igem.org
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<img id="klammer_gross_links" src="https://static.igem.org/mediawiki/2013/e/e0/Freiburg_2013_main2_Rahmen_gross_links.png"> | <img id="klammer_gross_links" src="https://static.igem.org/mediawiki/2013/e/e0/Freiburg_2013_main2_Rahmen_gross_links.png"> | ||
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<p id="text_gross" align="left"> Abstract </p> | <p id="text_gross" align="left"> Abstract </p> | ||
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The regulation is based on the RNA-guided Cas9 protein, which allows targeting of specific DNA sequences. | The regulation is based on the RNA-guided Cas9 protein, which allows targeting of specific DNA sequences. | ||
Our toolkit comprises not only a standardized Cas9 protein, but also different effector domains for | Our toolkit comprises not only a standardized Cas9 protein, but also different effector domains for | ||
- | efficient gene activation or repression. </div> | + | efficient gene activation or repression. |
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<img id="cas" src="https://static.igem.org/mediawiki/2013/9/94/Freiburg_2013_main2_Cas.png"> | <img id="cas" src="https://static.igem.org/mediawiki/2013/9/94/Freiburg_2013_main2_Cas.png"> | ||
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<img id="klammer_klein_rechts" src="https://static.igem.org/mediawiki/2013/8/82/Freiburg_2013_main2_Rahmen_gross_rechts.png"> | <img id="klammer_klein_rechts" src="https://static.igem.org/mediawiki/2013/8/82/Freiburg_2013_main2_Rahmen_gross_rechts.png"> | ||
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<img id="klammer_klein_rechts" src="https://static.igem.org/mediawiki/2013/8/82/Freiburg_2013_main2_Rahmen_gross_rechts.png"> | <img id="klammer_klein_rechts" src="https://static.igem.org/mediawiki/2013/8/82/Freiburg_2013_main2_Rahmen_gross_rechts.png"> | ||
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+ | HUMAN PRACTICE | ||
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Revision as of 14:00, 27 September 2013
Abstract Our Team developed a universal toolkit, termed uniCAS, that enables customizable gene regulation in mammalian cells. Therefore, we engineered the recently discovered and highly promising CRISPR/Cas9 system. The regulation is based on the RNA-guided Cas9 protein, which allows targeting of specific DNA sequences. Our toolkit comprises not only a standardized Cas9 protein, but also different effector domains for efficient gene activation or repression. |
Our Project
|
Highlights |
Toolkit Use our Toolkit to regulate your genes! |
HP Our Team developed... |
Team Our Team developed... |