Team:Michigan/Modeling

From 2013.igem.org

(Difference between revisions)
(→Switch Model)
(→Inducible Hbif Model)
Line 108: Line 108:
=[[Team:Michigan/Modeling/Inducible Hbif Model|Inducible Hbif Model]]=
=[[Team:Michigan/Modeling/Inducible Hbif Model|Inducible Hbif Model]]=
-
[[File:InducedHbif.jpg|center]]
+
 
[[File:InducibleHbifModelFigure.png|center]]
[[File:InducibleHbifModelFigure.png|center]]
Equation:
Equation:
Line 129: Line 129:
Optimization of ON:
Optimization of ON:
[[File:InducibleHbifModel7-2.png |347px|center]]
[[File:InducibleHbifModel7-2.png |347px|center]]
 +
 +
[[File:InducedHbif.jpg|center]]
[https://docs.google.com/document/d/1PNIkP84ksvYOu-HDYZghVVDkhDlMX7Iz9T6sFZnmfr8/edit?usp=sharing Inducible Hbif Model (Link)]
[https://docs.google.com/document/d/1PNIkP84ksvYOu-HDYZghVVDkhDlMX7Iz9T6sFZnmfr8/edit?usp=sharing Inducible Hbif Model (Link)]

Revision as of 23:19, 27 September 2013

Xayona Website Template

Overview Introduction Expression Model Switch Model Inducible Hbif Model Future Directions

Contents

Overview

Best model.jpg

Model of Recombinase Expression

Model of the Switch

Model of Inducible Hbif

Introduction

switch modeling

• goals: produce both states of switch, use model to optimize switch

mass action modeling

• what is mass action

• pros of mass action modeling, i.e. why we used it

• form of mass action models/solvability doc

analytical modeling:

• benefits 

   • naturally standardized
   
   • given parameters, it precisely predicts behavior

   • accurately predicts the data needed to determine parameters

   • allows avoidance of numerical errors like rounding

• ERSESCO 

   • equation

   • reduction

   • solution

   • equilibration

   • stabilization

   • calibration

   • optimization

File:Solvability.pdf

Expression Model

ExpressionModelFigure.png

Equation:

ExpressionModel1.png

Reduction: None

Solution:

ExpressionModel2.png

Equilibration:

ExpressionModel3.png

Stabilization:

ExpressionModel3-1.png

Calibration:

ExpressionModel4.png
ExpressionModel5.png

Optimization:

ExpressionModel6.png
Expression.jpg

Expression Model (Link)

Switch Model

SwitchModelFigure.png

Equation:

SwitchModel1.png
SwitchModel2.png

Reduction:

SwitchModel3.png

Solution:

SwitchModel3-1.png

Equilibration:

SwitchModel4-1.png

Stabilization:

SwitchModel4-2.png

Calibration:

SwitchModel5-1.png
SwitchModel5-2.png

Optimization:

SwitchModel6.png
Switch.jpg

Switch Model (Link)

Inducible Hbif Model

InducibleHbifModelFigure.png

Equation:

InducibleHbifModel1.png
InducibleHbifModel2.png

Reduction:

InducibleHbifModel3.png

Solution:

InducibleHbifModel4.png

Equilibration:

InducibleHbifModel5.png

Stabilization:

InducibleHbifModel5-2.png

Calibration:

InducibleHbifModel6-1.png
InducibleHbifModel6-2.png
InducibleHbifModel6-3.png

Optimization of Hbif:

InducibleHbifModel7-1.png

Optimization of ON:

InducibleHbifModel7-2.png
InducedHbif.jpg

Inducible Hbif Model (Link)

Future Directions

Data!

This is a template page. READ THESE INSTRUCTIONS.
You are provided with this team page template with which to start the iGEM season. You may choose to personalize it to fit your team but keep the same "look." Or you may choose to take your team wiki to a different level and design your own wiki. You can find some examples HERE.
You MUST have all of the pages listed in the menu below with the names specified. PLEASE keep all of your pages within your teams namespace.


Home Team Official Team Profile Project Parts Submitted to the Registry Modeling Notebook Safety Attributions
Retrieved from "http://2013.igem.org/Team:Michigan/Modeling"