Team:Penn/MaGellinFutureDirections
From 2013.igem.org
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- | Alternative to ChIP. MaGellin can also be used to screen the binding specificity of transcription factors (TF) and other DNA binding domains, with methylation serving as an effective reporter for targeted binding. | + | <i>Alternative to ChIP.</i> MaGellin can also be used to screen the binding specificity of transcription factors (TF) and other DNA binding domains, with methylation serving as an effective reporter for targeted binding. |
By fusing a TF to the methyltransferase, its binding with the plasmid becomes easily detected by the associated methylation | By fusing a TF to the methyltransferase, its binding with the plasmid becomes easily detected by the associated methylation |
Revision as of 02:37, 28 September 2013