Project Overview

Why CRISPRi?

• Regulate genomic genes without changing their promoters.

• "Totipotent"! Change the target gene as you want by making some minor changes in gRNA sequence.

Why Lights?

• Easy to adjust! Get rid of those laborious work of adding inducing chemicals! :)

• Multi-control! lights of different colors can be exerted simultaneously. And one sensor will only be activated by photons with a narrow range of wavelengths.

• Accurate!

• Uniformly distribute in cell culture.

Why CRISPRi AND Light?

• Light alone? CANNOT be easily applied on genomic genes.

• CRISPRi alone? HARD to be simultaneous; NOT convenient.

Why Computer?

Computer and Electronics! Experience the information century!

• Input your desired expression level into the computer. And just leave the rest to our program and illuminating device to adjust to your specific requirement.