Team:UCSF/About Us1

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Thanks a lot to 2012 Calgary team for snippets of their code!
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Thanks a lot to the 2011 Brown-Stanford and 2012 Lethbridge iGEM teams for snippets of their code!
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Check out their wikis at:
Check out their wikis at:
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https://2012.igem.org/Team:Lethbridge
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<h1><center><b>UCSF is a graduate institution - so where do UCSF iGEM team members come from?</h1></b></center> <p>
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<h2><FONT COLOR="#008000">Biotechnology Program at Abraham Lincoln High School (ALHS)</h2></FONT COLOR="#008000"> <p>
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The ALHS Biotechnology Program is a two year pathway developed by George Cachianes and co-taught by Julie Reis: <span class="textlink "><a href="http://www.lincolnhigh.net/academy/biotech/overview">Lincoln High Biotech Webpage </a><span></h4>
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This year, five members of the UCSF iGEM team were chosen from students who have completed this two-year class. Read more about David, Derrick, Eric, Sherry and Felicity at the <a href="https://2013.igem.org/Team:UCSF/Team"> team members page</a>! </regulartext></p>
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<h2><FONT COLOR="#008000">Peking University and UCSF iGEM Exchange</h2> </FONT COLOR="#008000"><p>
 
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<p>Through funding from QB3 and the Center for Systems and Synthetic Biology, we have established an exchange program with Peking University. For the past few years, we have welcomed an undergraduate student from PKU to join our team and vice versa. This summer, we had a student from the 2011 PKU iGEM team, JI Weiyue, join us for three months to work with as a part of our team. We also had a former UCSF iGEM member, Helena Viets, travel to Peking University and join the PKU iGEM team. </p>
 
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<h4>Priyanka Dadlani is a member of the Cal Teach program at UC Berkeley and joined us for 10 weeks this summer and worked on computational models to provide predictions that would guide our experimental strategy. To read more about Calteach, <a href="http://calteach.berkeley.edu/">visit the Cal Teach Webpage </a><span> </h4>
 
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<h2><FONT COLOR="#008000">HHMI EXROP</h2> </FONT COLOR="#008000"><p>
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<p>Ian Ergui joined us this summer as part of the Howard Hughes Medical Institute Exceptional Research Opportunities Program (EXROP). This program seeks to link students from disadvantaged backgrounds and students from groups that are underrepresented in the sciences to HHMI investigators from across the country. Students are given the opportunity to conduct research and live at an institution other than their home institution in order to experience science in a new academic setting. </p>
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        <span>Attributions</span>
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        <a href="https://2013.igem.org/Team:UCSF/Project/Attribute1">Attributions</a>
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        <span>Accomplishments</span>
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        <a href="https://2013.igem.org/Team:UCSF/Project/Accomplish1">Accomplishments</a>
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        <span>Implications</span>
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        <a href="https://2013.igem.org/Team:UCSF/Project/Implications1">Implications</a>
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        <span>Safety</span>
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        <a href="https://2013.igem.org/Team:UCSF/Safety1">Safety</a>
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<h2><center> Broader Implications for Our Project </center></h2>
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<p2>At the beginning of the summer, we discussed working on a project that would somehow benefit and help meet the demand of food for the growing population. A current issue that came to mind was the rise of antibiotic resistant bacterial strains found within a microbiome. We currently know that the most common response to a bacterial infection within a plant (or human) is to completely treat the entire microbiome with antibiotics. The negative effects of this response is that both the harmful and beneficial bacteria are killed during this process. An ethical issue we took into consideration was the increasing resistance against the creation and implication of GMO food within our food supply. <br><br>
 +
Our project addresses this growing issue by specifically targeting harmful bacteria within a diverse bacterial community by utilizing the CRISPR system along with bacterial conjugation as a delivery system. Our project is not yet complete and is not yet fit for field testing, but it has the potential of providing an alternative to the current use of antibiotics for this issue. By avoiding the use of antibiotics to eliminate an unwanted strain of bacteria in a microbiome, the possibility of antibiotic resistant strains being created would dramatically decrease. We are optimistic and hope that this project can create alternatives to current methods of indiscriminate treatment with antibiotics. <br><br>
 +
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 +
 
 +
<p1>
 +
Media References: <br>
 +
<a href="http://www.cnn.com/2013/09/16/health/antibiotic-resistant-infections-cdc/index.html" >CDC sets threat levels for drug-resistant 'superbugs'</a><br>
 +
<a href="http://www.sciencedaily.com/releases/2005/07/050705010900.htm" >Agricultural Antibiotic Use Contributes To 'Super-Bugs' In Humans</a>
 +
</p1>
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Revision as of 18:19, 28 October 2013

Broader Implications for Our Project

At the beginning of the summer, we discussed working on a project that would somehow benefit and help meet the demand of food for the growing population. A current issue that came to mind was the rise of antibiotic resistant bacterial strains found within a microbiome. We currently know that the most common response to a bacterial infection within a plant (or human) is to completely treat the entire microbiome with antibiotics. The negative effects of this response is that both the harmful and beneficial bacteria are killed during this process. An ethical issue we took into consideration was the increasing resistance against the creation and implication of GMO food within our food supply.

Our project addresses this growing issue by specifically targeting harmful bacteria within a diverse bacterial community by utilizing the CRISPR system along with bacterial conjugation as a delivery system. Our project is not yet complete and is not yet fit for field testing, but it has the potential of providing an alternative to the current use of antibiotics for this issue. By avoiding the use of antibiotics to eliminate an unwanted strain of bacteria in a microbiome, the possibility of antibiotic resistant strains being created would dramatically decrease. We are optimistic and hope that this project can create alternatives to current methods of indiscriminate treatment with antibiotics.

Media References:
CDC sets threat levels for drug-resistant 'superbugs'
Agricultural Antibiotic Use Contributes To 'Super-Bugs' In Humans

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