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Team:Evry/Modeling
From 2013.igem.org
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The modeling part is planned around 4 main targets: | The modeling part is planned around 4 main targets: | ||
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For a better understanding of the bacteria our team is going to produce, we chose to first focus on the growth of an iron-chelating bacterial population. | For a better understanding of the bacteria our team is going to produce, we chose to first focus on the growth of an iron-chelating bacterial population. | ||
<br/>Let us suppose we have <math>N_0</math> initial siderophore-producing bacterias in a closed system with dissolved iron. Monitoring the evolution of those bacterias, the dissolved iron, the siderophores and the chelated iron through a simple model will help our biologists tune their constructions.<br/><br/> | <br/>Let us suppose we have <math>N_0</math> initial siderophore-producing bacterias in a closed system with dissolved iron. Monitoring the evolution of those bacterias, the dissolved iron, the siderophores and the chelated iron through a simple model will help our biologists tune their constructions.<br/><br/> | ||
Revision as of 12:34, 18 July 2013
Modeling:
- Growth of an iron-chelating bacterial population
- Risk assessment : forecast, control, auto-regulation, ...
- Bacterial activity : iron-chelation rate, avidity (cellular scale)
- Intestine mapping and interactions
First approach:
Let us suppose we have initial siderophore-producing bacterias in a closed system with dissolved iron. Monitoring the evolution of those bacterias, the dissolved iron, the siderophores and the chelated iron through a simple model will help our biologists tune their constructions.
where α is the Mc Kellar adaptation factor:
