"
Team:EPF Lausanne
From 2013.igem.org
Mareikeapelt (Talk | contribs) |
|||
| Line 1: | Line 1: | ||
{{Template:EPFL2013}} | {{Template:EPFL2013}} | ||
| + | Taxi-Coli: “smart drug delivery” | ||
| + | |||
| + | Researchers all over the world strive to improve the effectiveness of drugs. Emergent strategies such as "Targeted drug delivery" allow a more precise and localized administration of drugs. The aim of this method is to increase drug concentration in a specific location (e.g. a tumor); yet decreasing secondary effects on healthy tissues. This method reduces the frequency and dose of drug administration. | ||
| + | |||
| + | EPFL team’s goal this year is to suggest a drug delivery strategy. The key word of this project is “adaptability”. Our motivation is to explore a way of using E.Coli as a drug carrier in a way that is highly modular; thereby suiting several applications and possibilities of disease treatment. | ||
| + | |||
| + | Using the principles of synthetic biology we will bond nanoparticles containing a drug to E.coli using the biotin-streptavidin interaction. The engineered E.coli will target the site where the drug is required. Upon stimuli it starts to release a protease degrading the nanoparticles and hence delivers the drug | ||
<!-- *** What falls between these lines is the Alert Box! You can remove it from your pages once you have read and understood the alert *** | <!-- *** What falls between these lines is the Alert Box! You can remove it from your pages once you have read and understood the alert *** | ||
Revision as of 11:56, 9 August 2013
| Home | Team | Official Team Profile | Project | Parts Submitted to the Registry | Coupling | Modeling | Notebook | Safety | Attributions |
|---|
Taxi-Coli: “smart drug delivery”
Researchers all over the world strive to improve the effectiveness of drugs. Emergent strategies such as "Targeted drug delivery" allow a more precise and localized administration of drugs. The aim of this method is to increase drug concentration in a specific location (e.g. a tumor); yet decreasing secondary effects on healthy tissues. This method reduces the frequency and dose of drug administration.
EPFL team’s goal this year is to suggest a drug delivery strategy. The key word of this project is “adaptability”. Our motivation is to explore a way of using E.Coli as a drug carrier in a way that is highly modular; thereby suiting several applications and possibilities of disease treatment.
Using the principles of synthetic biology we will bond nanoparticles containing a drug to E.coli using the biotin-streptavidin interaction. The engineered E.coli will target the site where the drug is required. Upon stimuli it starts to release a protease degrading the nanoparticles and hence delivers the drug
Blaa
Bla
Blaa
Bla
| You can write a background of your team here. Give us a background of your team, the members, etc. Or tell us more about something of your choosing. |  |
|
Tell us more about your project. Give us background. Use this as the abstract of your project. Be descriptive but concise (1-2 paragraphs) |  Your team picture |
| Team EPF_Lausanne |
