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From 2013.igem.org

NOTE: This part should contain an introduction to how cool silk is an why it is so good as an coating product (Silk vs collagen)

Silk

Silk is a natural protein fibre that is known for its use in textiles. The best known silk comes from the silk moth pupa but a lot of animals such as arthropods are also capable of producing silk. One of the arthropods well known for its silk is the spider. A

The properties of silk

The unique properties of silk are a result of its highly constant and repetitive amino-acid structure. The sequence of amino-acids determines what secondary structures will arise, and thus the final preferred protein conformation. The secondary structures may be beta sheets, beta-spirals, and beta-helices, of which the sheets realize the silk's amazing tensile strength, and the spirals and helices its elongation.

In the figure below a stress-strain diagram can be found (Frank K. Ko, et at. 2001) where Clavipus spider silk is compared to, Kevlar 29, normal silkworm silk, PET (polyethylene terephthalate), Nylon 6, and Merino wool. The stress-strain diagram relates the degree of deformation to the amount of energy absorbed.

A final general property of silk it that it can be integrated with the human body - it will not induce an immune response - potentially making it an ideal choice for many biomedical applications. Its compatibility extends to the gastrointestinal tract, that is, it is even safe to eat!

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Applications for silk

Silk's journey as a product began as luxurious clothing reserved exclusively for the emperor subsequent to its initial discovery. As the sericulture developed, however, it was soon adopted by all classes of society. New applications were discovered, and it was spun into many different products; fishing lines, musical instruments, and bowstrings to name a few. It's utility and value were also recognized by other kingdoms, and a world-wide, ever increasing demand for the material began. Indeed, the western demand for silk was so great, that the main set of trade routes between Europe and Asia became known as the Silk Road.

.... Nowadays, the variety of silk applications is even more extensive; bullet-proof clothing, all sorts of ropes and cables, artificial tendons and ligaments, bandages, sewing thread, seat belts, parachutes, biodegradable bottles, and much more.....

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   Silk
   Silk Secretion
   Coating Mechanism
   Backbone

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