Team:Uppsala/modeling

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Modeling

In the beginning of the project we asked ourselves what we wanted from a modelling project. After some contemplation, we arrived at the decision of making two models of quite different nature.


Mathematical modeling of p-coumaric acid pathway

The goal of the first model was to create a means of making practical predictions about the systems we were about to create, and thus make better design decisions in order to achieve an optimal metabolite yield. This required a more sophisticated model that took into concideration all the complex parameters influencing a biological system. In the end, we managed to arrive to a model that did just that for the metabolic pathway producing p-Coumeric acid.

>conceptbild från emils modell<

The model for p-Coumeric acid production can be found here [embedded link o p-Coumeric acid model]


Modeling for Dummies

Our second goal with this year’s modelling project was to provide a more easy-to-access model aimed mainly at future iGEM teams. We found that while there are many excellent modelling contributions from earlier teams out there, the level of understanding required to take advantage of the information provided is quite high. Seeing as iGEM is an undergraduate competition, and not everyone participating have the requisite experience with systems like MATLAB, we figured that providing a comprehensive tutorial coupled with a simple model made within the bounds of a user-friendly interface would be a good contribution to this year’s modelling project.

>Typ fig. 11 i tutorial<

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