Team:Heidelberg/Templates/Modelling/Ind-Production
From 2013.igem.org
Challenge
Based on coupled ordinary differential equations (ODEs). Mathematical modelling allows forApproach
The ODE system determining the time evolution of the dynamical variables is given by the following four equations:$$ \mathrm{d}\mathrm{[Bac]}/\mathrm{d}t = -\frac{\mathrm{[Bac]} \cdot \left(\mathrm{[Bac]} - \mathrm{Bacmax\_native\_svp}\right) \cdot \left(\mathrm{beta\_native\_svp} - \mathrm{[Ind]} \cdot \mathrm{ki\_native\_svp}\right)}{\mathrm{Bacmax\_native\_svp}} $$ $$\mathrm{d}\mathrm{[Glu]}/\mathrm{d}t = - \mathrm{[Bac]} \cdot \mathrm{[Glu]} \cdot \mathrm{ksyn\_native\_svp} $$ $$\mathrm{d}\mathrm{[cGlu]}/\mathrm{d}t = - \mathrm{kdim\_native\_svp} \cdot {\mathrm{[cGlu]}}^2 - \mathrm{kdegg\_native\_svp} \cdot \mathrm{[cGlu]} + \mathrm{[Bac]} \cdot \mathrm{[Glu]} \cdot \mathrm{ksyn\_native\_svp} $$ $$\mathrm{d}\mathrm{[Ind]}/\mathrm{d}t = {\mathrm{[cGlu]}}^2 \cdot \mathrm{kdim\_native\_svp} - \mathrm{[Ind]} \cdot \mathrm{kdegi\_native\_svp} $$