To create a means of communication from cell to machine, we chose the red fluorescence protein KillerRed as a reporter protein. The first condition that our device needs to fulfill is to record light intensity. Then it needs to generate fluorescence thank to a light source and a couple of excitation and emission filters. Firstly we will explain the choice of the different components, then the several experiences we did to find the most accurate parameters for each part of the device – the photodiode, Arduino, and the optic.