Team:Paris Bettencourt

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FIGHT TUBERCULOSIS WITH MODERN WEAPONS

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis affecting millions of people over the world. Using Escherichia coli as a model organism we are developing different approaches that could contribute to the fight against TB.

A biosensor that detects the presence of sequence specific antibiotic resistance genes.

A safe and specific high-throughput drug screening method that targets essential mycobacterial metabolic proteins.

A phage system with low fitness cost producing sRNA, which inhibit the synthesis of antibiotic resistance proteins.

An E. coli which invades macrophages and kills mycobacteria.
Detect
Target
Infiltrate
Sabotage
Our results here

Centre for Research and Interdisciplinarity (CRI)
Faculty of Medicine Cochin Port-Royal, South wing, 2nd floor
Paris Descartes University
24, rue du Faubourg Saint Jacques
75014 Paris, France
+33 1 44 41 25 22/25
team2013@igem-paris.org
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