Team:Carnegie Mellon/Modeling

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Killer Red






Modeling

We developed two models, each of which characterizes our experimental system on a different scale. The intracellular model uses chemical kinetics to model transcription and translation of the KillerRed gene, maturation of KillerRed, and the photochemistry of superoxide radical production. The phage-host dynamics model examines the interactions between E. coli and $\lambda$ and characterizes the effect of KillerRed (or control mRFP) on the system.



Model of KillerRed synthesis and superoxide production

Model of host-phage dynamics