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From 2013.igem.org

Contents 1 Section VI. Take Home Essay 1.1 What is immunological tolerance? 1.1.1 self tolerance 1.1.2 induced tolerance 1.1.2.1 central tolerance 1.1.2.2 peripheral tolerance 1.1.2.3 acquired tolerance 1.2 How do our Immune system recognize and destroy Cancer cells

Section VI. Take Home Essay

What is immunological tolerance?

immunological tolerance also called immune toleranceTemplate loop detected: Template:LangWithName,it is mean the immune system do not response to the specific antigen. It can divided into self toleranceTemplate loop detected: Template:LangWithName & induced toleranceTemplate loop detected: Template:LangWithName.

self tolerance

生物體對自身體細胞的抗原不會產生反應

induced tolerance

對外來抗原不會產生免疫反應，是通過誘導的方式產生。induced tolerance又可分為central toleranceTemplate loop detected: Template:LangWithName、peripheral toleranceTemplate loop detected: Template:LangWithName與acquired toleranceTemplate loop detected: Template:LangWithName。

central tolerance

The tolerance produced at this stage of B-cell development is known as central tolerance because it arises in a central lymphoid organ, the bone marrow.

peripheral tolerance

self-reactive B cells that

escape this test and go on to mature may still be removed from the repertoire after they have left the bone marrow, a process that produces peripheral tolerance.

acquired tolerance

How do our Immune system recognize and destroy Cancer cells

reference:

1. Janeway's Immunobiology 8th
2. Wiki