Team:Heidelberg/Templates/NRPS-W-14

From 2013.igem.org

Database redesign

The domains are now saved all in one table and they each have a domain type specified. Due to this setup the database can now also cover modification domains.

GUI extension

The php scripts were extended to allow for entries to the new database. Additionally an XML export funciton was added to the design interface.

Draft of PFAM querying

In the experimental parts, we determined a first rough estimate of NRPS domain boundaries based on Pfam. Thus we also wanted our software to use the Pfam predictions to make it easier to semi-automatically add new domains into our database. A first test Python script was written which queried the Pfam API using the Requests library according to the online documentation and then parsed the XML output. The Biopython library also proved to be of great help.