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From 2013.igem.org

a.tooltip { outline:none; text-decoration:none; border-bottom:dotted 1px blue; }

a.tooltip strong {

line-height:30px; }

a.tooltip > span {
width:200px;
padding: 10px 20px;
margin-top: 20px;
margin-left: -85px;
opacity: 0;
visibility: hidden;
z-index: 10;
position: absolute;
font-family: Arial;
font-size: 12px;
font-style: normal;
-webkit-border-radius: 3px;
-moz-border-radius: 3px;
-o-border-radius: 3px;
border-radius: 3px;
-webkit-box-shadow: 2px 2px 2px #999;
-moz-box-shadow: 2px 2px 2px #999;
box-shadow: 2px 2px 2px #999;
-webkit-transition-property:opacity, margin-top, visibility, margin-left;
-webkit-transition-duration:0.4s, 0.3s, 0.4s, 0.3s;
-webkit-transition-timing-function: ease-in-out, ease-in-out, ease-in-out, ease-in-out;
-moz-transition-property:opacity, margin-top, visibility, margin-left;
-moz-transition-duration:0.4s, 0.3s, 0.4s, 0.3s;
-moz-transition-timing-function: ease-in-out, ease-in-out, ease-in-out, ease-in-out;
-o-transition-property:opacity, margin-top, visibility, margin-left;
-o-transition-duration:0.4s, 0.3s, 0.4s, 0.3s;
-o-transition-timing-function: ease-in-out, ease-in-out, ease-in-out, ease-in-out;
transition-property:opacity, margin-top, visibility, margin-left;
transition-duration:0.4s, 0.3s, 0.4s, 0.3s;
transition-timing-function: ease-in-out, ease-in-out, ease-in-out, ease-in-out;
}
/*a.tooltip > span:hover,*/ a.tooltip:hover > span {
opacity: 1;
text-decoration:none;
visibility: visible;
overflow: visible;
margin-top:50px;
display: inline;
margin-left: -60px;
}
a.tooltip span b {
width: 15px;
height: 15px;
margin-left: 20px;
margin-top: -19px;
display: block;
position: absolute;
-webkit-transform: rotate(-45deg);
-moz-transform: rotate(-45deg);
-o-transform: rotate(-45deg);
transform: rotate(-45deg);
-webkit-box-shadow: inset -1px 1px 0 #fff;
-moz-box-shadow: inset 0 1px 0 #fff;
-o-box-shadow: inset 0 1px 0 #fff;
box-shadow: inset 0 1px 0 #fff;
display: none\0/;
*display: none;
}
a.tooltip > span {
color: #000000;
background: #66CCFF;
background: -moz-linear-gradient(top, #66CCFF 0%, #FFFFFF 100%);
background: -webkit-gradient(linear, left top, left bottom, color-stop(0%,#66CCFF), color-stop(100%,#FFFFFF));
filter: progid:DXImageTransform.Microsoft.gradient( startColorstr='#66CCFF', endColorstr='#FFFFFF',GradientType=0 );
border: 1px solid #000099;
}
a.tooltip span b {
background: #66CCFF;
border-top: 1px solid #000099;
border-right: 1px solid #000099;
}