KillSwitch

From 2013.igem.org

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<h2 align="center">Differential Equations</h2>
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The kill switch circuit can be represented by the following equations.<br>
 
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The kill switch circuit can be represented by the following differential equations. </p>
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Revision as of 11:12, 16 August 2013

Kill Switch

The kill switch design is based on the expression of holin and antiholin, Figure 1. Holin is a protein that forms pores in cell membranes. Anti-holin binds to holin and inhibits it's action. Once pores are formed by holin, lysozyme can access the periplasmic space and degrade the cell wall, causing cell lysis.

Kill switch constitutes a crucial part of our final system. It is activated after the production and release of the antimicrobial peptide. In that way, E.coli is killed and the safety of the system is ensured.

Figure 1: Circuit of the kill switch

Differential Equations

The kill switch circuit can be represented by the following differential equations.