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| - | {{Team:BGU_Israel/header}}
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| - | <html>
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| - | <!-- MAIN -->
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| - | <span class="title">Title</span>
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| - | <span class="subtitle">******</span>
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| - | <img src="https://static.igem.org/mediawiki/2013/d/db/BGU_01.jpg" title= "About 60 years ago, David Ben-Gurion, Israel's fisrt prime minister, had a vision of developing the Negev desert.</br> <i>"It is in the Negev that the creativity and pioneer vigor of Israel will be tested"</i>" alt="" />
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| - | <img src="https://static.igem.org/mediawiki/2013/7/74/BGU_02.jpg" title="In 1969, his dream became a reality. Ben-Gurion Univeristy (BGU) was established in the Negev desert." alt="" />
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| - | <img src="https://static.igem.org/mediawiki/2013/4/4f/BGU_03.jpg" title="BGU's exelence in engineering, research and science is a fullfilment of Ben-Gurion's vision. </br> As Ben-Gurion has stated:<i>" It is incumbent upon our researchers to focus on new areas of research "</i> " alt="" />
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| - | <img src="https://static.igem.org/mediawiki/2013/d/d7/BGU_04.jpg" title="In 2013, the pioneer iGEM BGU is established. </br> Our creative innovation is a scientific breakthrough and will have a great effect on the future of science. " alt="" />
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| - | <p>The processes of bioremediation, biosensors and bio-medicine often require the release of genetically modified organisms (GMO's) to the environment. After being released, these GMO's are no longer under direct control, therefore posing potential threats such as substituting the natural bacterial population, horizontal gene transfer, and lastly, creating public concern and opposition to the field of genetic engineering.<br/><br/>
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| - | In order to overcome these issues, we are designing a genetic circuit that limits the lifetime of a bacterial population after it is released into the environment. Our ultimate goal is to allow the end user to program a GMO population to survive in the environment until it has completed its task, after which the entire population will disappear. Crucially, our mechanism will function independently, without any external intervention. <br/><br/>
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| - | We are approaching this goal from two angles: <strong>"P.A.S.E 1" </strong>is based on the dilution of a vital component through cell division, while <strong> "P.A.S.E 2" </strong> is based on the lifetime of an essential protein. The two methods utilize novel mechanisms such as a recombination cassette, the innovative use of an unnatural amino acid (UAA) in a biologic gate, and more. We also intend to introduce new biobricks that will be useful for a wide range of purposes, including bacterial genome incorporation parts and UAA incorporation machinery. This project will be the first modular, independent and generic bacterial control system. <br/><br/>
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| - | We want our construct to pave the way to a safe synthetic revolution: one that will allow developers to innovate and create freely without arousing public opposition or harming the environment. <br/><br/>
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| - | </p>
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| - | <iframe width="420" height="315" src="http://www.youtube.com/embed/p3zuIQ3I5O8" frameborder="0" allowfullscreen></iframe>
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| - | <div id="topics1">
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| - | <iframe width="420" height="315" src="http://www.youtube.com/embed/p3zuIQ3I5O8" frameborder="0" allowfullscreen></iframe>
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| - | <a href="problem.html">
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| - | <img class="topic-pic" src="./images/BGU_topic-problem.png" />
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| - | <div class="topics-text">
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| - | <h6>The Problem</h6>
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| - | <p>Can synthetic biology become a hazard? </p>
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| - | <a href="Solution.html">
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| - | <img class="topic-pic" src="./images/BGU_topic-solution.png" />
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| - | <div class="topics-text">
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| - | <h6>Our Solution</h6>
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| - | <p> Read more about P.A.S.E </p>
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| - | </div>
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| - | </a>
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| - | <a href="results.html">
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| - | <img class="topic-pic1" src="./images/BGU_topic-results.png" />
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| - | <div class="topics-text1">
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| - | <h6>Human Practice</h6>
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| - | <p>Follow our unconventional activities</p>
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| - | <a href="experiments.html">
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| - | <img class="topic-pic" src="./images/BGU_topic-notebook.png" />
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| - | <div class="topics-text">
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| - | <h6>Notebook</h6>
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| - | <p>Follow our experiments, from start to finish.</p>
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| - | </div>
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| - | </a>
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| - | </td>
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| - | <a href="team.html">
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| - | <img class="topic-pic" src="./images/BGU_topic-team.png" />
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| - | <div class="topics-text">
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| - | <h6>The Team</h6>
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| - | <p>Meet the people behind the project</p>
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| - | </div>
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| - | </a>
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| - | <!-- ENDS MAIN -->
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| - | </body>
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| - | {{Team:BGU_Israel/footer}}
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