Team:GeorgiaTech

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                The objective for our project is ultimately to express human integrins on the surface of E.Coli cells.  By expressing
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                human integrins on bacteria cells, we can manipulate the cells to respond to specific stimuli in their environment. The
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                specific integrin we are trying to express on the E.Coli cell has the ability to bind to fibrinogen. If it is successfully placed
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                on the cell, the cell will be able to bind to fibrinogen, effectively coagulating or clotting blood. This has applications in the
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                medical field, where the integrin-containing E.Coli (BioBots, as we like to call them) can be administered as a topical solution
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                and prevent excessive bleeding on major surface wounds.  A bacteria’s ability to express integrins has other applications as
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                well. Since the bacteria will be able to send and receive signals to its environment, the bacteria can theoretically detect and
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                locate cancer cells, as well as any other specific cell or structure of concern. These novel bacterial robots will represent the
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                first prokaryotic use of heterodimeric integrins for a sensory function and will represent a platform that will enable future
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                “design” of integrins sensory function through molecular evolution techniques.
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         <div id ="menu" style ="display:none; position:absolute" ><p class =" textLarge">Menu</p></div>
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                     <a href="https://2013.igem.org/Team:GeorgiaTech" style ="font-size:80px; padding-top:8px;padding-bottom:8px">
                     <a href="https://2013.igem.org/Team:GeorgiaTech" style ="font-size:80px; padding-top:8px;padding-bottom:8px">
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                         <img src = "https://static.igem.org/mediawiki/2013/f/f0/GeorgiaTech_team.png" class = "smallLogo" alt ="GT iGEM logo"></img>Home
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                         <img src = "https://static.igem.org/mediawiki/2013/f/f0/GeorgiaTech_team.png" class = "smallLogo" alt ="GT iGEM logo"/>Home
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                <li><a href="https://2013.igem.org/Team:GeorgiaTech/Objective" style ="padding-top:8px;padding-bottom:8px">Objective</a></li>
                 <li><a href="https://2013.igem.org/Team:GeorgiaTech/Team" style ="padding-top:8px;padding-bottom:8px">Team</a></li>
                 <li><a href="https://2013.igem.org/Team:GeorgiaTech/Team" style ="padding-top:8px;padding-bottom:8px">Team</a></li>
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                 <li><a href="https://2013.igem.org/Team:GeorgiaTech/Project" style ="padding-top:8px;padding-bottom:8px">Project</a></li>
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                 <li><a href="https://2013.igem.org/Team:GeorgiaTech/Project" style ="padding-top:8px;padding-bottom:8px">Projects</a></li>
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                <li><a href="https://2013.igem.org/Team:GeorgiaTech/Parts" style ="padding-top:8px;padding-bottom:8px">Protocols</a></li>
                 <li><a href="https://2013.igem.org/Team:GeorgiaTech/Parts" style ="padding-top:8px;padding-bottom:8px">Parts</a></li>
                 <li><a href="https://2013.igem.org/Team:GeorgiaTech/Parts" style ="padding-top:8px;padding-bottom:8px">Parts</a></li>
                 <li><a href="https://2013.igem.org/Team:GeorgiaTech/Safety" style ="padding-top:8px;padding-bottom:8px">Safety</a></li>
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                 <li><a href="https://2013.igem.org/Team:GeorgiaTech/Attributions" style ="padding-top:8px;padding-bottom:8px">Attributions</a></li>
                 <li><a href="https://2013.igem.org/Team:GeorgiaTech/Attributions" style ="padding-top:8px;padding-bottom:8px">Attributions</a></li>
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                 <li><a href="https://2013.igem.org/Team:GeorgiaTech/Parts" style ="padding-top:8px;padding-bottom:8px">High School Project</a></li>
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                 <li><a href="https://2013.igem.org/Team:GeorgiaTech/Human_Practices" style ="padding-top:8px;padding-bottom:8px">Human Practices</a></li>
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<li><a href="https://2013.igem.org/Team:GeorgiaTech/Objective" style ="padding-top:8px;padding-bottom:8px">Objective</a></li>
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                 <li><a id ="return" href="#" style ="padding-top:8px;padding-bottom:8px">RETURN</a></li>
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Revision as of 23:56, 27 September 2013

Georgia Tech iGEM