Team:Goettingen/Achievement

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Revision as of 16:45, 3 October 2013





The beast and its Achilles heel:

 A novel target to fight multi-resistant pathogenic bacteria


Team: Goettingen

Region: Europe

iGEM Year: 2013

Track: Health & Medicine

Project Name: The beast and its Achilles heel: A novel target to fight multi-resistant bacteria


Project Abstract:

Since the discovery of penicillin by Alexander Fleming in 1928, antibiotics have marked a major victory of mankind in the battle against infectious diseases. However, after 90 years, the antibiotics are now losing their old time glory: Bacteria acquire resistance against antibiotics and become unbridled. We must control the use of antibiotics, meanwhile, we need new antibiotics, which can sufficiently eliminate the invaders without hurting the "good" bacteria. Therefore, c-di-AMP, an important, recently discovered signaling molecule in gram-positive bacteria, has come to our sight. Our project is to build a screening system targeting c-di-AMP, which could be applied in novel-drug screening. With this system, the level of c-di-AMP in the cell can be visualized and measured.


Achievements

We have:

Goe-%E2%88%9A.JPEG Register the team, have a great summer, and plan to have fun at the Regional Jamboree.

Goe-%E2%88%9A.JPEG Successfully complete and submit this iGEM 2013 Judging form.

Goe-%E2%88%9A.JPEG Create and share a Description of the team's project using the iGEM wiki and the team's parts using the Registry of Standard Biological Parts.

Goe-%E2%88%9A.JPEG Plan to present a Poster and Talk at the iGEM Jamboree.

Goe-%E2%88%9A.JPEG Document at least one new standard BioBrick Part or Device used in your project/central to your project and submit this part to the iGEM Registry (submissions must adhere to the iGEM Registry guidelines). A new application of, and outstanding documentation (quantitative data showing the Part's/ Device's function), of a previously existing BioBrick part in the 'Experience' page of that part's Registry entry also counts. Please note you must submit this new part to the iGEM Registry.

For all our parts, we have accomlished:

Goe-%E2%88%9A.JPEG Description of function

Goe-%E2%88%9A.JPEG Quantitative data showing the Part or Device function

Goe-%E2%88%9A.JPEG Acknowedgment of sources and references




We have also:

Goe-%E2%88%9A.JPEG experimentally validate that at least one new BioBrick Part or Device of your own design and construction works as expected.

Goe-%E2%88%9A.JPEG document the characterization of this part in the 'Main Page' of that Part's/Device's Registry entry. Submit new parts to the iGEM Parts Registry.

For our parts, we have also fulfilled

Goe-%E2%88%9A.JPEG Description of function

Goe-%E2%88%9A.JPEG Quantitative data showing the Part or Device function

Goe-%E2%88%9A.JPEG Acknowedgment of sources and references

Goe-%E2%88%9A.JPEG considered the safety issues and filled in the safe forms.





We have also:

Goe-%E2%88%9A.JPEG improve the function of an existing BioBrick Part or Device (created by another team or your own institution in a previous year), enter this information in the 'Experience' section of that Parts's Registry entry), create a new registry page for the improved part, and submit this part to the iGEM Registry. See Team:Goettingen/Parts Parts

For all improved parts, we fulfilled:

Goe-%E2%88%9A.JPEG Description of function

Goe-%E2%88%9A.JPEG Quantitative data showing the Part or Device function

Goe-%E2%88%9A.JPEG Acknowedgment of sources and references

Goe-%E2%88%9A.JPEG Help any registered iGEM team from another school or institution by, for example, characterizing a part, debugging a construct, or modeling or simulating their system.